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Top 9 Accelerators and Incubators in Houston (2026)

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Houston's startup ecosystem is supported by a diverse group of accelerators and incubators. These programs focus on key local industries such as healthcare, energy, and enterprise software.

Among them, TMCx Accelerator has helped almost 20 healthcare companies get started. Softeq Venture Fund is another key player, with over 15 investments in software and hardware.

Below is our list of the best 9 accelerators and incubators in Houston.

Failory's Top 9 Picks

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Through its Digital Catalyst Program, Hewlett Packard Enterprise identifies and co-innovates with the next generation of digital disruptors in the Indian startup ecosystem. The program provides startups with crucial support and access to HPE's technology and market channels to accelerate their growth.

Year Founded2020
Founders
Nº of Investments12
Nº of Exits2

As part of the world's largest medical city, TMCx helps breakthrough digital health and medical device startups navigate the complex healthcare industry. The program provides unparalleled access to clinical expertise and a vast network of hospital partners, helping founders validate and scale their innovations.

Year Founded2014
Founders
Nº of Investments19
Nº of Exits2

Softeq Venture Fund invests in and partners with early-stage tech startups, providing them with crucial seed funding and mentorship. Their venture studio model uniquely offers hands-on, full-stack engineering support to help founders build and launch complex products in hardware, IoT, and AI.

Year Founded1997
FoundersBret Siarkowski, Chris Howard, Joel Carter
Nº of Investments17
Nº of Exits1
Program TypeOn-Site
Duration (Weeks)12

Dedicated to fostering a flourishing ecosystem of African innovators, Innovest Afrika empowers entrepreneurs through critical resources and mentorship. The non-profit focuses on helping early-stage, socially-minded founders build sustainable businesses that can solve pressing challenges across the continent.

Year Founded
Founders
Nº of Investments2
Nº of Exits

Eunike Ventures champions technology startups aiming to innovate within the oil and gas industry. They provide a crucial bridge, connecting emerging software and AI companies with established energy corporations to fast-track commercialization.

Year Founded2017
FoundersThomas Henry, Amy Henry
Nº of Investments1
Nº of Exits

Halliburton Labs helps advance the future of energy by supporting early-stage companies focused on clean and affordable solutions. Participants gain access to Halliburton's industrial-scale capabilities, deep expertise, and global network to accelerate their path to market.

Year Founded2020
FoundersScott Gale
Nº of Investments10
Nº of Exits

The Cannon Community cultivates a powerful ecosystem for entrepreneurs through its combination of flexible workspace and a digital resource hub. They focus on connecting startups with a network of mentors and peers, providing the physical and virtual infrastructure needed for business growth.

Year Founded2017
FoundersLawson Gow
Nº of Investments
Nº of Exits

As a lead investor, Indus River Ventures focuses on funding early-stage medical device companies. Their support extends beyond capital, providing startups with access to specialized programs, platforms, and devices to accelerate their growth.

Year Founded2015
Founders
Nº of Investments1
Nº of Exits

Acting as a strategic bridge, Wazobia Investments facilitates market entry for companies expanding into Africa and for African businesses targeting the United States. Their expertise in business development and project management helps clients navigate the complexities of international commerce.

Year Founded2009
FoundersDamilola Agboola, Michael Oluwagbemi
Nº of Investments
Nº of Exits

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