This free sheet contains 100 accelerators and incubators you can apply to today, along with information about the industries they generally invest in.
This free sheet contains all the information about the top 100 unicorns, including their valuation, HQ's location, founded year, name of founders, funding amount and number of employees.
This free Notion document contains the best 100+ resources you need for building a successful startup, divided in 4 categories: Fundraising, People, Product, and Growth.
Palo Alto is home to 35 unicorn startups, with a strong focus on artificial intelligence and deep tech. The city continues to be a major center for high value technology companies.
The local scene includes Safe Superintelligence, which reached a $32B valuation in its founding year. Other major players like Glean and PsiQuantum are each valued at $7B.
Below is the full list of 35 Palo Alto unicorn startups at this time.
Everything you need to raise funding for your startup, including 3,500+ investors, 7 tools, 18 templates and 3 learning resources.
Buy It For $97 $297 →Information about the industries, countries, and cities they generally invest in.
Get the Sheet for $50Information about their valuation, HQ's location, founded year, name of founders, funding amount and number of employees.
Get the Sheet for $50List of startup investors in the BioTech, Health, and Medicine industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50List of 250 startup investors in the AI and Machine Learning industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50List of 250 startup investors in the FinTech and Finance industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50Safe Superintelligence was founded with the singular mission of building artificial intelligence that is inherently safe. Their team approaches this by treating safety not as an afterthought, but as the central technical problem to be solved.
Glean builds a generative AI work assistant that searches across all of a company's applications. This unified search helps employees instantly find information and discover knowledge from across the entire organization.
PsiQuantum is building a fault-tolerant quantum computer using a silicon photonics platform. This approach uses light particles as qubits and is designed to scale using conventional semiconductor manufacturing.
ClickHouse builds an open-source, column-oriented database for real-time analytical reporting. Their system is recognized for its high performance, allowing users to run complex SQL queries on massive datasets with extremely low latency.
SandboxAQ develops enterprise software that combines AI and quantum technology to solve complex computational problems. Their solutions are applied across industries like cybersecurity, biopharma, and materials science to enhance security and accelerate research.
Binance.US offers a digital asset marketplace for buying, selling, and trading a wide range of cryptocurrencies. The platform provides a secure and compliant exchange built specifically for customers in the United States.
SambaNova develops an integrated hardware and software platform for enterprise-level artificial intelligence. Their full-stack system is designed to run complex AI models across the entire lifecycle, from training to inference.
Hippocratic AI is building a generative AI for healthcare that prioritizes patient safety. The technology is designed to take on non-diagnostic tasks, helping to reduce costs and improve health equity.
Inflection AI built Pi, a personal AI created to be empathetic and supportive. The AI studio is now pivoting to an API-first strategy to make its powerful language models widely available to developers.
Aptos Labs is the team behind a Layer 1 blockchain designed for safe, scalable, and upgradeable Web3 infrastructure. They provide the foundation for developers to build decentralized applications and ecosystems for mainstream adoption.
The top ten companies are just part of the story in Palo Alto. Dozens of other startups are tackling big problems in fields like AI and healthcare, raising over $7.5 billion to fund their work.
Some are early in their journey while others are already well known. Here’s a look at the rest of the unicorn startups shaping the city.
| Unicorn Startup | Main Industry | Year Founded | Amount Raised | Valuation |
|---|---|---|---|---|
| Design | 2009 | $613.6M | $4B | |
| Marketing | 2014 | $667.1M | $4B | |
| AI | 2008 | $880.9M | $3B | |
| Hardware | 2015 | $722.4M | $3B | |
| AI | 2018 | $270.2M | $2.2B | |
| Healthcare | 2015 | $506.6M | $2.1B | |
| Crypto | 2013 | $171.5M | $2B | |
| AI | 2020 | $195M | $2B | |
| AI | 2022 | $380M | $2B | |
| Crypto | 2021 | $336M | $2B | |
| Biotech | 2019 | $921.3M | $2B | |
| Crypto | 2018 | $115M | $2B | |
| Infrastructure | 2011 | $435.9M | $2B | |
| AI | 2017 | $276M | $2B | |
| Media | 2014 | $73.7M | $2B | |
| AI | 2015 | $271M | $1.4B | |
| AI | 2022 | $435M | $1.25B | |
| AI | 2020 | $150.8M | $1.15B | |
| Mobility | 2025 | $305M | $1B | |
| AI | 2014 | $236.5M | $1B | |
| AI | 2022 | $165M | $1B | |
| SaaS | 2018 | $182.2M | $1B | |
| Analytics | 2012 | $195.5M | $1B | |
| Fintech | 2008 | $274.2M | $1B | |
| Fintech | 2019 | — | $1B |
