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The Founder's Handbook
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The Perfect Pitch Deck
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100 Accelerators & Incubators
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This free sheet contains 100 VC firms, with information about the countries, cities, stages, and industries they invest in, as well as their contact details.

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100 Top Unicorns

Top 3 Venture Capital Firms in Ann Arbor (2026)

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Ann Arbor has a surprisingly busy venture capital scene, with firms like Arboretum Ventures backing over 110 companies. RPM Ventures is also quite active, with nearly 100 investments and over 20 exits.

With several active investors in town, it can be tough to know who to pitch first. We've highlighted the top firms to help you get started.

Below is our list of the best 3 VC firms in Ann Arbor.

Failory's Top 3 Picks

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Arboretum Ventures backs healthcare startups developing medical devices, diagnostics, and health IT to improve patient care and lower costs. The firm manages $700 million in capital and partners with companies from seed to later stages, guiding them toward successful outcomes like the SI-BONE IPO.

Year Founded2002
FoundersJan Garfinkle, Tim Petersen
Investment StageEarly Stage, Late Stage, Post-Ipo, Private Equity, Seed
Nº of Investments111 (49 as Lead Investor)
Nº of Exits25 (6 IPO'd)
Contactinfo@arboretumvc.com / (734) 998-3688

RPM Ventures backs early-stage founders aiming to disrupt massive markets in FinTech, InsurTech, and Real Estate Tech. They bring deep expertise to their portfolio, particularly within the mobility and transportation sectors where they are established thought leaders.

Year Founded2000
FoundersMarc Weiser
Investment StageEarly Stage, Late Stage, Seed
Nº of Investments94 (24 as Lead Investor)
Nº of Exits22 (4 IPO'd)
Contactinfo@rpmvc.com / (734) 332-1700

Plymouth Growth partners with B2B software and technology companies across the mid-continent that are already generating $3M to $10M in revenue and are ready to scale. The firm brings decades of operational experience to the table, partnering with capital-efficient entrepreneurs to help them grow their teams and businesses effectively.

Year Founded2003
FoundersIan Bund
Investment StageEarly Stage, Late Stage, Private Equity
Nº of Investments62 (36 as Lead Investor)
Nº of Exits13 (2 IPO'd)
Contactatodak@plymouthgp.com / (734) 747-9401

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