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The Founder's Handbook

Top 39 Biotechnology Unicorns in 2024

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The Biotechnology industry is filled with successful companies that have raised millions of dollars in VC funding that came from some of the top investors in the world.

Many of these successes have turned into unicorns — private companies worth over $1 billion.

If you want to build the next unicorn in the Biotechnology space, these 39 companies should be your inspiration.

39 Biotechnology Unicorns Companies

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2,189 Accelerators & Incubators

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1,016 Unicorns

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1) Biosplice Therapeutics

Biosplice Therapeutics

Biosplice Therapeutics is developing tissue-level regeneration technologies that will be used in the fields of functional medicine and regenerative medicine.

Details of the startup:

  • Valuation: $12.00B (August 2018)
  • Country: United States
  • State: California
  • City: San Diego
  • Started in: 2008
  • Founders: Osman Kibar
  • Number of employees: 50-100
  • Funding: $285.71M
  • Funding rounds: 6
  • Number of investors: 12

You can find their website here.

2) Tempus

Tempus

Our unique, AI-based technologies have the potential to transform healthcare and significantly advance precision medicine.

Details of the startup:

  • Valuation: $8.10B (March 2018)
  • Country: United States
  • State: Illinois
  • City: Chicago
  • Started in: 2015
  • Founders: Eric Lefkofsky
  • Number of employees: 1,000-5,000
  • Funding: $1,070.00M
  • Funding rounds: 11
  • Number of investors: 10

You can find their website here.

3) Caris Life Sciences

Caris Life Sciences

Caris Life Sciences enhances precision medicine by providing information about a patient's health to clinicians.

Details of the startup:

  • Valuation: $7.83B (May 2021)
  • Country: United States
  • State: Texas
  • City: Irving
  • Started in: 1996
  • Founders: David D. Halbert
  • Number of employees: 1,000-5,000
  • Funding: $1,314.49M
  • Funding rounds: 5
  • Number of investors: 19

You can find their website here.

4) Benchling

Benchling

Benchling is a cloud-based software platform for biologists and companies engaged in research and development.

Details of the startup:

  • Valuation: $6.10B (April 2021)
  • Country: United States
  • State: California
  • City: San Francisco
  • Started in: 2012
  • Founders: Ashutosh Singhal, Cory Li, Sajith Wickramasekara
  • Number of employees: 500-1,000
  • Funding: $412.00M
  • Funding rounds: 8
  • Number of investors: 21

You can find their website here.

5) Color

Color

Color is a clinical genetics company that makes it possible to streamline the process of gathering genetic data.

Details of the startup:

  • Valuation: $4.60B (January 2021)
  • Country: United States
  • State: California
  • City: Burlingame
  • Started in: 2013
  • Founders: Elad Gil, Nish Bhat, Othman Laraki, Taylor Sittler
  • Number of employees: 500-1,000
  • Funding: $496.04M
  • Funding rounds: 9
  • Number of investors: 35

You can find their website here.

6) Intarcia Therapeutics

Intarcia Therapeutics

Intarcia is a biotechnology company focused solely on the development of long-duration therapies to treat chronic diseases.

Details of the startup:

  • Valuation: $3.80B (April 2014)
  • Country: United States
  • State: Massachusetts
  • City: Boston
  • Started in: 1995
  • Founders: David Franklin, James M. Ahlers, Thomas Alessi
  • Number of employees: 250-500
  • Funding: $1,683.53M
  • Funding rounds: 23
  • Number of investors: 27

You can find their website here.

7) Abogen Biosciences

Abogen Biosciences

Abogen Biosciences is a biotechnology company in the discovery phase that focuses on the development of nucleic acid-based RNA and DNA therapeutics.

Details of the startup:

  • Valuation: $3.70B (November 2021)
  • Country: China
  • State: Jiangsu
  • City: Suzhou
  • Started in: 2019
  • Founders: James Nightingale
  • Number of employees: 501-1000
  • Funding: $1,400.00M
  • Funding rounds: 33
  • Number of investors: 2

You can find their website here.

8) Eikon Therapeutics

Eikon Therapeutics

Eikon Therapeutics is a biopharmaceutical company that specialises in live-cell resolution microscopy and drug discovery engineering.

Details of the startup:

  • Valuation: $3.20B (January 2022)
  • Country: United States
  • State: California
  • City: Hayward
  • Started in: 2019
  • Founders: Eric Betzig, Luke Lavi, Robert Tjian, Xavier Darzacq
  • Number of employees: 251-500
  • Funding: $666.00M
  • Funding rounds: 3
  • Number of investors: 18

You can find their website here.

9) Freenome

Freenome

Freenome is a biotechnology company that has developed a comprehensive multiomics platform for cancer detection using a simple blood draw.

Details of the startup:

  • Valuation: $2.62B (August 2020)
  • Country: United States
  • State: California
  • City: South San Francisco
  • Started in: 2014
  • Founders: Charles Roberts, Gabriel Otte, Michael Otte, Riley Ennis
  • Number of employees: 251-500
  • Funding: $1,097.55M
  • Funding rounds: 8
  • Number of investors: 50

You can find their website here.

10) Eat Just

Eat Just

EAT JUST is inspiring a global shift in perception towards veganism and plant- based foods.

Details of the startup:

  • Valuation: $2.59B (November 2017)
  • Country: United States
  • State: California
  • City: San Francisco
  • Started in: 2011
  • Founders: Josh Balk, Josh Tetrick
  • Number of employees: 100-250
  • Funding: $303.10M
  • Funding rounds: 12
  • Number of investors: 39

You can find their website here.

11) Motif

Motif

Motif is a company that specialises in food technology.

Details of the startup:

  • Valuation: $2.20B (June 2021)
  • Country: United States
  • State: Massachusetts
  • City: Boston
  • Started in: 2019
  • Founders: Jonathan McIntyre
  • Number of employees: 11-50
  • Funding: $343.50M
  • Funding rounds: 4
  • Number of investors: 20

You can find their website here.

12) Preferred Networks

Preferred Networks

Preferred Networks specializes in building AI-led solutions that automate and optimize your business processes. They build real-world solutions that solve complex industry problems with cutting-edge technologies including deep learning, robotics and advanced analytics.

Details of the startup:

  • Valuation: $2.00B (May 2018)
  • Country: Japan
  • City: Tokyo
  • Started in: 2014
  • Founders: Daisuke Okanohara, Morikawa Hiroyuki, Nishitoba Jiro, Toru Nishikawa
  • Number of employees: 250-500
  • Funding: $152.19M
  • Funding rounds: 7
  • Number of investors: 11

You can find their website here.

13) XtalPi

XtalPi

XtalPi is a software development company that takes drug R&D and uses artificial intelligence, machine learning, and artificial neural networks to create compounds that are more effective and cheaper to develop.

Details of the startup:

  • Valuation: $2.00B (August 2021)
  • Country: China
  • State: Guangdong
  • City: Shenzhen
  • Started in: 2014
  • Founders: Jian Ma, Lipeng Lai, Shuhao Wen
  • Number of employees: 50-100
  • Funding: $342.37M
  • Funding rounds: 10
  • Number of investors: 22

You can find their website here.

14) Solugen

Solugen

Solugen is a specialty chemicals ​manufacturer creating chemistries that are safe, cost-effective, and environmentally-friendly.

Details of the startup:

  • Valuation: $2.00B (September 2021)
  • Country: United States
  • State: Texas
  • City: Houston
  • Started in: 2016
  • Founders: Gaurab Chakrabarti, Sean Hunt
  • Number of employees: 100-250
  • Funding: $443.07M
  • Funding rounds: 7
  • Number of investors: 23

You can find their website here.

15) Apeel Sciences

Apeel Sciences

Apeel Sciences is accelerating the preservation of fresh produce with plant-derived shelf life extension technology.

Details of the startup:

  • Valuation: $2.00B (May 2020)
  • Country: United States
  • State: California
  • City: Goleta
  • Started in: 2012
  • Founders: James Rogers
  • Number of employees: 500-1,000
  • Funding: $640.00M
  • Funding rounds: 9
  • Number of investors: 30

You can find their website here.

16) ConcertAI

ConcertAI

ConcertAI is a healthcare AI-powered SaaS data company that creates medical research tools in oncology.

Details of the startup:

  • Valuation: $1.90B (March 2022)
  • Country: United States
  • State: Massachusetts
  • City: Cambridge
  • Started in: 2018
  • Founders: Jeff Elton, Romesh Wadhwani
  • Number of employees: 1001-5000
  • Funding: $300.00M
  • Funding rounds: 2
  • Number of investors: 5

You can find their website here.

17) Opentrons

Opentrons

OpenTrons is a developer of a pipetting robot technology designed to automate experiments.

Details of the startup:

  • Valuation: $1.80B (September 2021)
  • Country: United States
  • State: New York
  • City: Brooklyn
  • Started in: 2016
  • Founders: Chiu Chau, Nicholas Wagner, Will Canine
  • Number of employees: 250-500
  • Funding: $250.83M
  • Funding rounds: 8
  • Number of investors: 11

You can find their website here.

18) Cambrian BioPharma

Cambrian BioPharma

Cambrian is a distributed development company that creates therapeutics to help people live longer lives.

Details of the startup:

  • Valuation: $1.79B (October 2021)
  • Country: United States
  • State: New York
  • City: New York
  • Started in: 2019
  • Founders: Christian Angermayer, James Peyer, Sebastian Brunemeier
  • Number of employees: 11-50
  • Funding: $160.00M
  • Funding rounds: 3
  • Number of investors: 16

You can find their website here.

19) Tessera Therapeutics

Tessera Therapeutics

Tessera Therapeutics is a biotechnology firm specialising in a new class of genetic medicines.

Details of the startup:

  • Valuation: $1.69B (April 2022)
  • Country: United States
  • State: Massachusetts
  • City: Cambridge
  • Started in: 2018
  • Founders: Geoffrey von Maltzahn, Jacob Rubens
  • Number of employees: 101-250
  • Funding: $531.76M
  • Funding rounds: 3
  • Number of investors: 13

You can find their website here.

20) Orna Therapeutics

Orna Therapeutics

Orna Therapeutics is a biotechnology company that focuses on fully engineered circular RNA therapeutics for the treatment of various diseases.

Details of the startup:

  • Valuation: $1.50B (August 2022)
  • Country: United States
  • State: Massachusetts
  • City: Cambridge
  • Started in: 2019
  • Founders: Alex Wesselhoeft, Daniel Anderson, Raffaella Squilloni
  • Number of employees: 51-100
  • Funding: $321.00M
  • Funding rounds: 3
  • Number of investors: 10

You can find their website here.

21) Athelas

Athelas

Athelas creates technology that enables chronically ill people to be monitored in their homes.

Details of the startup:

  • Valuation: $1.50B (January 2022)
  • Country: United States
  • State: California
  • City: Mountain View
  • Started in: 2016
  • Founders: Deepika Bodapati, Tanay Tandon
  • Funding: $136.08M
  • Funding rounds: 4
  • Number of investors: 16

You can find their website here.

22) Inari

Inari

Inari presents high performing plant varieties that improve the economic and environmental realities of production agriculture.

Details of the startup:

  • Valuation: $1.50B (May 2021)
  • Country: United States
  • State: Massachusetts
  • City: Cambridge
  • Started in: 2016
  • Founders: David Berry, Ignacio Martinez, Laura Lande-Diner
  • Number of employees: 100-250
  • Funding: $397.00M
  • Funding rounds: 4
  • Number of investors: 11

You can find their website here.

23) Generate Biomedicines

Generate Biomedicines

Generate Biomedicines is a biotech company dedicated to developing ground-breaking medicines.

Details of the startup:

  • Valuation: $1.36B (November 2021)
  • Country: United States
  • State: Massachusetts
  • City: Somerville
  • Started in: 2018
  • Founders: Geoffrey von Maltzahn, Gevorg Grigoryan, Molly Gibson
  • Number of employees: 251-500
  • Funding: $420.00M
  • Funding rounds: 2
  • Number of investors: 8

You can find their website here.

24) Alzheon

Alzheon

Alzheon is a biotechnology company developing therapies for brain function, memory and aging.

Details of the startup:

  • Valuation: $1.31B (September 2020)
  • Country: United States
  • State: Massachusetts
  • City: Framingham
  • Started in: 2013
  • Founders: Martin Tolar
  • Number of employees: 10-50
  • Funding: $94.40M
  • Funding rounds: 7
  • Number of investors: 3

You can find their website here.

25) Biofourmis

Biofourmis

Biofourmis is a biotechnology company that uses digital therapeutics to enhance personalised care and therapies.

Details of the startup:

  • Valuation: $1.30B (April 2022)
  • Country: United States
  • State: Massachusetts
  • City: Boston
  • Started in: 2015
  • Founders: Kuldeep Singh Rajput, Maulik Majmudar, Wendou Niu
  • Number of employees: 101-250
  • Funding: $463.57M
  • Funding rounds: 10
  • Number of investors: 15

You can find their website here.

26) HeartFlow

HeartFlow

HeartFlow is a new revolutionary diagnostic tool. It combines ultrasound imaging and artificial intelligence to non-invasively diagnose and detect myocardial fibrosis, a physical condition of the heart muscle that can lead to heart failure.

Details of the startup:

  • Valuation: $1.30B (December 2017)
  • Country: United States
  • State: California
  • City: Redwood City
  • Started in: 2007
  • Founders: Charles A. Taylor, Christopher K. Zarins
  • Number of employees: 250-500
  • Funding: $281.00M
  • Funding rounds: 10
  • Number of investors: 10

You can find their website here.

27) InSightec

InSightec

InSightec develops and manufactures MR-guided Focused Ultrasound devices for image-guided acoustic surgery. Their technology is based on patented Focused Ultrasound principles, and was designed to replace surgery.

Details of the startup:

  • Valuation: $1.30B (March 2020)
  • Country: Israel
  • City: Tirat Carmel
  • Started in: 1999
  • Founders: Kobi Vortman
  • Number of employees: 250-500
  • Funding: $559.05M
  • Funding rounds: 10
  • Number of investors: 9

You can find their website here.

28) EQRx

EQRx

EQRx is a biotechnology company specializing in turning existing drugs into generic versions with greater clinical utility.

Details of the startup:

  • Valuation: $1.23B (January 2021)
  • Country: United States
  • State: Massachusetts
  • City: Cambridge
  • Started in: 2020
  • Founders: Alexis Borisy, Peter Bach, Sandra Horning
  • Number of employees: 250-500
  • Funding: $700.00M
  • Funding rounds: 3
  • Number of investors: 21

You can find their website here.

29) Kallyope

Kallyope

Kallyope is pioneering the science and understanding of gut and gut-brain biology to transform human health.

Details of the startup:

  • Valuation: $1.22B (February 2022)
  • Country: United States
  • State: New York
  • City: New York
  • Started in: 2015
  • Founders: Charles Zuker, Richard Axel, Tom Maniatis
  • Number of employees: 101-250
  • Funding: $479.00M
  • Funding rounds: 5
  • Number of investors: 18

You can find their website here.

30) Spiber

Spiber

Spiber is a Japanese biomaterials company engaged in the research of synthetic spider silk and other protein-based materials.

Details of the startup:

  • Valuation: $1.22B (September 2021)
  • Country: Japan
  • City: Tsuruoka
  • Started in: 2007
  • Founders: Kazuhide Sekiyama, Sugawara Junichi
  • Number of employees: 100-250
  • Funding: $911.62M
  • Funding rounds: 17
  • Number of investors: 21

You can find their website here.

31) Prime Medicine

Prime Medicine

Prime Medicine operates as a biotechnology company that delivers the promise of gene editing using Prime Editing.

Details of the startup:

  • Valuation: $1.20B (July 2021)
  • Country: United States
  • State: Massachusetts
  • City: Cambridge
  • Started in: 2019
  • Founders: Andrew Anzalone, David R. Liu, Jeremy Duffield
  • Number of employees: 50-100
  • Funding: $150.93M
  • Funding rounds: 2
  • Number of investors: 12

You can find their website here.

32) Spectrum Medical

Spectrum Medical

Perfusion Systems and EMR Systems are global leaders.

Details of the startup:

  • Valuation: $1.20B (July 2022)
  • Country: United Kingdom
  • State: Gloucestershire
  • City: Gloucester
  • Started in: 2006
  • Founders: Mark Drain, Steve Turner
  • Number of employees: 51-100

You can find their website here.

33) Aprogen

Aprogen

Aprogen is a biotechnology company delivering innovative and cost-effective solutions to patients.

Details of the startup:

  • Valuation: $1.04B (May 2019)
  • Country: South Korea
  • City: Seongnam-Si
  • Started in: 2000
  • Founders: Jaeseob Kim
  • Number of employees: 10-50
  • Funding: $62.12M
  • Funding rounds: 1
  • Number of investors: 1

You can find their website here.

34) TrialSpark

TrialSpark

TrialSpark is a technology company that helps bring treatments to patients faster by reimagining how clinical trials are run.

Details of the startup:

  • Valuation: $1.00B (September 2021)
  • Country: United States
  • State: New York
  • City: New York
  • Started in: 2014
  • Founders: Benjamine Liu, Kit Dobyns, Linhao Zhang
  • Number of employees: 100-250
  • Funding: $238.30M
  • Funding rounds: 3
  • Number of investors: 13

You can find their website here.

35) Owkin

Owkin

Founded in 2016, Owkin uses artificial intelligence to find the right treatment for every patient.

Details of the startup:

  • Valuation: $1.00B (November 2021)
  • Country: United States
  • State: New York
  • City: New York
  • Started in: 2016
  • Founders: Gilles Wainrib, Thomas Clozel
  • Number of employees: 100-250
  • Funding: $254.10M
  • Funding rounds: 7
  • Number of investors: 15

You can find their website here.

36) LetsGetChecked

LetsGetChecked

LetsGetChecked is an at-home health testing platform that connects customers to regulated laboratory testing.

Details of the startup:

  • Valuation: $1.00B (June 2021)
  • Country: Ireland
  • City: Dublin
  • Started in: 2015
  • Founders: Peter Foley
  • Number of employees: 500-1,000
  • Funding: $263.00M
  • Funding rounds: 4
  • Number of investors: 13

You can find their website here.

37) Mammoth Biosciences

Mammoth Biosciences

Mammoth Biosciences develops novel CRISPR applications for disease detection, research, agriculture, biodefense, and more.

Details of the startup:

  • Valuation: $1.00B (September 2021)
  • Country: United States
  • State: California
  • City: Brisbane
  • Started in: 2017
  • Founders: Ashley Tehranchi, Janice Chen, Jennifer Doudna, Lucas Harrington, Trevor Martin
  • Number of employees: 100-250
  • Funding: $279.69M
  • Funding rounds: 7
  • Number of investors: 26

You can find their website here.

38) iCarbonX

iCarbonX

iCarbonX offers a cutting-edge artificial intelligence platform for health data to increase the accuracy of predictions and to build a more predictive healthcare model based on human health data.

Details of the startup:

  • Valuation: $1.00B (April 2016)
  • Country: China
  • State: Guangdong
  • City: Shenzhen
  • Started in: 2015
  • Founders: Chun Wu, Hao Li, Jun Wang, Yingrui Li
  • Number of employees: 100-250
  • Funding: $306.16M
  • Funding rounds: 2
  • Number of investors: 3

You can find their website here.

39) Ynsect

Ynsect

Ynsect is a company that delivers innovative solutions for the agro-food and environmental biotechnology industries, by providing biological control products and services.

Details of the startup:

  • Valuation: $1.00B (February 2019)
  • Country: France
  • City: Evry
  • Started in: 2011
  • Founders: Alexis Angot, Antoine Hubert, Fabrice Berro, Jean-Gabriel Levon
  • Number of employees: 100-250
  • Funding: $393.40M
  • Funding rounds: 11
  • Number of investors: 23

You can find their website here.

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