Finding the right funding partner can feel like searching for a needle in a haystack, especially in a field as complex as biotechnology. But the right investor does more than just write a check; they become a crucial part of your team.
Firms like Andreessen Horowitz have backed nearly 1,800 companies, while Polaris Partners has seen over 200 of its portfolio companies exit. These are just a couple of the experienced VCs actively funding the next generation of biotech founders.
Below is our list of the best 54 Biotech VC firms.
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Buy It For $97 $297 →Andreessen Horowitz invests in technology companies from seed to late-stage, focusing on areas like software, biotech, crypto, and fintech. Beyond just capital, they offer extensive operational support to help build foundational companies, including successes like Coinbase, Lyft, and Github.
| Headquarters | Menlo Park, California, United States |
| Year Founded | 2009 |
| Founders | Ben Horowitz, Marc Andreessen |
| Total Funding | $32.4B |
| Average Check Size | $1M |
| Industries | Biotech, Healthcare, Crypto & Blockchain, Consumer, Enterprise, Fintech, Gaming |
| Investment Stage | Early Stage, Late Stage, Seed |
| Nº of Investments | 1791 (808 as Lead Investor) |
| Nº of Exits | 266 (43 IPO'd) |
| Top Portfolio Startups | Coinbase, Lyft, Github |
| Contact | menlopark-info@a16z.com / (650) 798-5800 |
Norwest backs companies from early to late stages with venture and growth equity, focusing on the consumer, enterprise, and healthcare sectors. With a portfolio of over 600 companies including Vertex Pharmaceuticals, they offer founders an extensive network and operational services to help scale their businesses.
| Headquarters | Palo Alto, California, United States |
| Year Founded | 1961 |
| Founders | Irem Rami, Jeff Crowe, Jon Kossow, Promod Haque, Sohil Chand |
| Total Funding | $12.6B |
| Average Check Size | $25M |
| Industries | Consumer, Enterprise, Healthcare, AI & ML, Biotech, DTC, E-Commerce, Education, Fintech, Food & Beverage, Marketplace, Media, SaaS, Proptech & Real Estate, Infrastructure |
| Investment Stage | Convertible Note, Debt, Early Stage, Late Stage, Private Equity, Secondary Market, Growth |
| Nº of Investments | 1000 (391 as Lead Investor) |
| Nº of Exits | 225 (42 IPO'd) |
| Top Portfolio Startups | Grove Collaborative, Sundaysky, Vertex Pharmaceuticals |
| Contact | businessplan@nvp.com / +1 650-321-8000 |
Lightspeed Venture Partners backs ambitious founders across the enterprise, consumer, and health sectors, supporting them from seed to late-stage growth. They have helped build category-defining companies, with a portfolio that includes breakout successes like Grubhub and Zscaler.
| Headquarters | Menlo Park, California, United States |
| Year Founded | 2000 |
| Founders | Barry Eggers, Christopher Schaepe, Peter Nieh, Ravi Mhatre |
| Total Funding | $18.9B |
| Average Check Size | $50M |
| Industries | Consumer, Enterprise, Health & Wellness, Crypto & Blockchain, Fintech, DTC, Education, Media, Social, SaaS, Big Data & Analytics, Biotech, Infrastructure |
| Investment Stage | Early Stage, Late Stage, Seed |
| Nº of Investments | 1566 (575 as Lead Investor) |
| Nº of Exits | 262 (40 IPO'd) |
| Top Portfolio Startups | Grubhub, Zscaler, Setu |
| Contact | info@lsvp.com / +1 650 234 8300 |
Draper Associates backs founders at the earliest stages, investing globally in companies set to transform industries from fintech and SaaS to aerospace. Their portfolio includes industry-defining companies like Tesla, SpaceX, and Coinbase, reflecting their mission to help build platforms for exceptional growth.
| Headquarters | San Mateo, California, United States |
| Year Founded | 2015 |
| Founders | Tim Draper |
| Total Funding | $230M |
| Industries | Government Technology, Life Sciences, Biotech, Food & Beverage, Crypto & Blockchain, Education, Energy, Fintech, Healthcare, Mobility, Legal, Aerospace & Space |
| Investment Stage | Crowdfunding, Early Stage, Non Equity Assistance, Private Equity, Seed |
| Nº of Investments | 436 (123 as Lead Investor) |
| Nº of Exits | 73 (7 IPO'd) |
| Top Portfolio Startups | Phantom Neuro, UnumID, sHMOODY |
| Contact | plans@draper.vc |
Backed by the Shenzhen Government, Shenzhen Capital Group funds high-tech enterprises and SMEs to help build China's national industries. They invest from seed to late-stage across sectors like IT, biopharma, and new energy, and have guided a large number of portfolio companies to public listings.
| Headquarters | Nanshan, Hunan, China |
| Year Founded | 1999 |
| Founders | Liu Can |
| Industries | Internet & Mobile, DTC, Climate & Sustainability, Supply Chain & Logistics, Biotech, Media, Manufacturing |
| Investment Stage | Early Stage, Late Stage, Seed |
| Nº of Investments | 702 (284 as Lead Investor) |
| Nº of Exits | 97 (91 IPO'd) |
| Contact | master@szvc.com.cn / 0755-82912888 |
Polaris Partners invests in healthcare and biotechnology companies, supporting founders from the earliest stages through growth. Their portfolio, which includes companies like Syros Pharmaceuticals, focuses on developing new care delivery models and life science platforms.
| Headquarters | Boston, Massachusetts, United States |
| Year Founded | 1996 |
| Founders | Jon Flint, Steve Arnold, Terrance McGuire |
| Total Funding | $4.5B |
| Average Check Size | $5M |
| Industries | Healthcare, Biotech |
| Investment Stage | Early Stage, Late Stage, Private Equity, Seed, Series A, Series B |
| Nº of Investments | 745 (215 as Lead Investor) |
| Nº of Exits | 203 (54 IPO'd) |
| Top Portfolio Startups | Gossamer Bio, Syros Pharmaceuticals, Neuronetics |
| Contact | partnership@polarispartners.com / +1 855 787 3500 |
With over $5 billion in assets, Lux Capital invests in deep tech and science-focused startups from their earliest stages, spanning sectors from AI and robotics to aerospace. They operate as active partners, having built over 20 companies internally and helping guide portfolio companies like Anduril and Planet to become leaders in their fields.
| Headquarters | New York, New York, United States |
| Year Founded | 2000 |
| Founders | Josh Wolfe, Peter Hebert, Rob Paull |
| Total Funding | $1.5B |
| Industries | Deep Tech & Hard Science, Robotics, Manufacturing, AI & ML, Biotech, Infrastructure, Energy, Fintech, Hardware, AR & VR, Transportation, Crypto & Blockchain, Aerospace & Space |
| Investment Stage | Debt, Early Stage, Late Stage, Private Equity, Seed |
| Nº of Investments | 569 (162 as Lead Investor) |
| Nº of Exits | 68 (17 IPO'd) |
| Top Portfolio Startups | Lumafield, Drone Racing, Novig |
| Contact | info@luxcapital.com / 646-349-2960 |
EQT Ventures backs ambitious founders across Europe, providing the capital and operational support its team of ex-operators wished they'd had on their own journeys. Using its proprietary AI platform, Motherbrain, the firm takes a data-driven approach to funding global success stories, including companies like Wolt.
| Headquarters | Stockholm, Stockholms Lan, Sweden |
| Year Founded | 2016 |
| Founders | Hjalmar Winbladh, Kees Koolen, Lars Jörnow |
| Total Funding | €1.4B |
| Average Check Size | €50M |
| Industries | Cybersecurity, Biotech, Social, Media, E-Commerce, AR & VR, AI & ML, Fintech, Gaming, Internet & Mobile, Developer Tools, Manufacturing, Automotive, SaaS |
| Investment Stage | Early Stage, Late Stage |
| Nº of Investments | 233 (134 as Lead Investor) |
| Nº of Exits | 25 (1 IPO'd) |
| Top Portfolio Startups | Peltarion, Verto Analytics, Nectarine Health |
Playground Global partners with technical and scientific founders to build companies in deep tech and life sciences, focusing on sectors from next-gen compute to engineered biology. They often serve as the first institutional check, helping launch ambitious ventures like Relativity Space, PsiQuantum, and MosaicML.
| Headquarters | Palo Alto, California, United States |
| Year Founded | 2015 |
| Founders | Bruce Leak, Matt Hershenson, Peter Barrett, Peter Barrett |
| Industries | AI & ML, Deep Tech & Hard Science, Life Sciences, Biotech, Healthcare, Automation, Robotics, Aerospace & Space |
| Investment Stage | Early Stage, Seed, Series A, Series B |
| Nº of Investments | 128 (59 as Lead Investor) |
| Nº of Exits | 16 (1 IPO'd) |
| Contact | info@playground.global / 650-427-0000 |
Correlation Ventures uses predictive analytics to make co-investment decisions in two weeks or less, helping entrepreneurs and their lead investors close financing rounds with greater speed and certainty. This data-driven approach enables them to back a broad portfolio of companies across all stages, which includes the AI lending platform Upstart.
| Headquarters | San Diego, California, United States |
| Year Founded | 2006 |
| Founders | David Coats, Trevor Kienzle |
| Total Funding | $360M |
| Average Check Size | $4M |
| Industries | Aerospace & Space, Biotech, Consumer, Healthcare, Hardware, Energy, Fintech, Industrial, Proptech & Real Estate, SaaS |
| Investment Stage | Early Stage, Late Stage, Seed, Series A, Growth |
| Nº of Investments | 410 (7 as Lead Investor) |
| Nº of Exits | 88 (12 IPO'd) |
| Top Portfolio Startups | Zebit, Virsto, Upstart |
| Contact | info@correlationvc.com / 650-353-3327 |
44 Additional Biotech VC Firms Worth Pitching
Our favorite funds are a great place to start, but they're far from the only ones backing biotech founders. The investors below have collectively backed over 10,000 startups and helped more than 2,000 of them reach an exit.
While many are based in the US, you'll find active firms everywhere from South Korea to Argentina. Here’s a look at the other venture capital firms funding what's next in biotech.
