The Windy City has a reputation for being down-to-earth, and its investment community is no different. For founders, this means access to capital without the coastal hype.
You'll find active firms like Second Century Ventures, with over 200 investments under its belt, and G Squared, which has guided almost 40 companies to an exit. Many others are writing checks for all kinds of startups.
Below is our list of the best 40 VC firms in Chicago.
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Buy It For $97 $297 →CMT Digital invests in early-stage companies within the crypto and blockchain industry. The firm supports its portfolio through a combination of venture funding, active asset trading, and expertise in the sector's legal and policy issues.
| Year Founded | 2017 |
| Founders | Colleen Sullivan, Jan-Dirk Lueders, Scott Casto |
| Investment Stage | Convertible Note, Early Stage, Seed |
| Nº of Investments | 202 (11 as Lead Investor) |
| Nº of Exits | 7 (3 IPO'd) |
| Contact | bitcoin@cmtam.com |
S2G Investments backs businesses from seed to late-stage that are transforming the food, agriculture, oceans, and energy sectors. With a portfolio including companies like Beyond Meat and sweetgreen, they focus on building a healthier and more sustainable planet through market-driven solutions.
| Year Founded | 2014 |
| Founders | Chuck Templeton, Sanjeev Krishnan, Victor Friedberg |
| Investment Stage | Convertible Note, Debt, Early Stage, Late Stage, Post-Ipo, Seed |
| Nº of Investments | 182 (83 as Lead Investor) |
| Nº of Exits | 9 (4 IPO'd) |
| Contact | 312-321-8000 |
Origin Ventures funds early-stage companies that use artificial intelligence to transform productivity and automation. The firm invests in the infrastructure, software, and marketplaces foundational to this AI-driven shift.
| Year Founded | 1999 |
| Founders | Bruce N. Barron, Steven N. Miller |
| Investment Stage | Early Stage, Seed |
| Nº of Investments | 125 (51 as Lead Investor) |
| Nº of Exits | 21 (1 IPO'd) |
| Contact | inquire@originventures.com |
G Squared provides capital throughout a venture's lifecycle, addressing the modern trend of companies staying private longer by offering both growth funding and liquidity for stakeholders. They have backed household names like Spotify, Instacart, and Lyft, partnering with entrepreneurs building disruptive, high-growth businesses.
| Year Founded | 2011 |
| Founders | Larry Aschebrook |
| Investment Stage | Convertible Note, Early Stage, Late Stage, Post-Ipo, Secondary Market, Seed |
| Nº of Investments | 111 (15 as Lead Investor) |
| Nº of Exits | 38 (27 IPO'd) |
| Contact | ir@gsquared.com / 312-552-7162 |
Second Century Ventures promotes innovation in the real estate industry by investing in promising technology startups. As the venture fund of the National Association of Realtors, it gives portfolio companies a distinct advantage through access to the association's vast network and resources.
| Year Founded | 2009 |
| Founders | Bob Goldberg, Dale Stinton |
| Investment Stage | Convertible Note, Early Stage, Late Stage |
| Nº of Investments | 208 (53 as Lead Investor) |
| Nº of Exits | 26 (3 IPO'd) |
| Contact | hello@secondcenturyventures.com / 312-329-8524 |
Sandbox Industries builds and manages businesses by connecting corporate partners with startups in healthcare, food, and agriculture. The firm creates dedicated venture funds and accelerator programs, such as with Blue Cross Blue Shield, to offer entrepreneurs both capital and strategic collaboration.
| Year Founded | 2003 |
| Founders | Cecelia Myers, Jonathan Pirc, Nicholas Rosa, Nick Rosa, Robert Shapiro, Ryan Schoop |
| Investment Stage | Early Stage, Late Stage, Private Equity, Seed |
| Nº of Investments | 96 (13 as Lead Investor) |
| Nº of Exits | 24 (3 IPO'd) |
| Contact | info@sandboxindustries.com / 312.228.4656 |
Impact Engine provides venture capital and private equity to early-stage companies generating positive outcomes in education, health, economic empowerment, and environmental sustainability. The firm supports purpose-driven founders who are building businesses to solve pressing social and environmental challenges.
| Year Founded | 2012 |
| Founders | Jamie Jones, Linda Darragh |
| Investment Stage | Convertible Note, Early Stage, Seed |
| Nº of Investments | 88 (1 as Lead Investor) |
| Nº of Exits | 7 |
| Contact | info@theimpactengine.com / +1 832-265-7550 |
Wind Point Partners acquires and develops middle-market businesses throughout North America. They build value by executing a strategy that combines initial platform acquisitions with numerous add-on acquisitions.
Chingona Ventures writes checks for pre-seed and seed-stage startups, with a focus on backing founders who are often overlooked by traditional venture capital. They invest in industries like fintech, health, and education, supporting companies such as Career Karma.
| Year Founded | 2019 |
| Founders | Samara Hernandez |
| Total Funding | $58M |
| Average Check Size | $1M |
| Industries | Fintech, Health & Wellness, Education |
| Investment Stage | Early Stage, Seed, Pre-Seed |
| Nº of Investments | 50 (10 as Lead Investor) |
| Nº of Exits | 6 (1 IPO'd) |
| Top Portfolio Startups | Boom, Blanket, Career Karma |
| Contact | admin@chingona.ventures |
With a 17-year track record, Moderne Ventures provides strategic capital to companies from early-stage through private equity. They are generalist investors with deep expertise in sectors like AI, robotics, and enterprise SaaS, backing technologies that can be applied across multiple industries for high growth.
| Year Founded | 2015 |
| Founders | Constance Freedman |
| Investment Stage | Early Stage, Late Stage, Private Equity |
| Nº of Investments | 105 (14 as Lead Investor) |
| Nº of Exits | 29 (3 IPO'd) |
| Contact | info@moderneventures.com |
30 Additional Chicago VC Firms Worth Pitching
Chicago's funding scene runs much deeper than our top picks. Combined, the city's other active VCs have backed nearly 2,000 startups and guided over 350 to an exit. This group includes both long-established players and newer funds getting started. Here’s a look at the other venture capital firms funding what's next in Chicago.