Philadelphia's startup scene is getting more attention, and for good reason. Firms like First Round Capital have backed nearly 1,000 companies, showing the depth of opportunity in the city.
From long-standing investors like Ben Franklin Technology Partners to newer funds with a specific focus, there is a wide range of capital available for founders. Finding the right partner is the first step toward building your company.
Below is our list of the best 10 VC firms in Philadelphia.
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Buy It For $97 $297 →First Round Capital operates as a seed-stage venture firm, backing technology entrepreneurs and helping build foundational companies like Uber, Square, and Warby Parker. They go beyond funding by building a strong community and offering custom software and services to help founders grow their businesses from the very beginning.
| Year Founded | 2004 |
| Founders | Howard Morgan, Josh Kopelman, Todd Jackson |
| Total Funding | $738M |
| Average Check Size | $4M |
| Industries | Consumer, Enterprise, Fintech, Healthcare, Hardware |
| Investment Stage | Debt, Early Stage, Late Stage, Seed, Series A |
| Nº of Investments | 976 (226 as Lead Investor) |
| Nº of Exits | 222 (16 IPO'd) |
| Top Portfolio Startups | Uber, Ring, Planet |
| Contact | info@firstround.com / (415) 646-0072 |
MissionOG backs high-growth companies with proven business models, focusing on financial services, payments, data platforms, and software. The team, composed of former operators, provides both financial capital and a network of industry experts to help their partner companies scale.
| Year Founded | 2012 |
| Founders | Andy Newcomb, Drew Kese, Gene Lockhart, George Krautzel, Kevin O'Nell |
| Investment Stage | Early Stage, Late Stage |
| Nº of Investments | 70 (32 as Lead Investor) |
| Nº of Exits | 17 (2 IPO'd) |
| Contact | info@missionog.com / (267) 239-5869 |
Aperture Venture Capital provides early-stage and seed funding to diverse founders creating financial innovations for the "Multicultural Mainstream." They support startups developing tools that help individuals and businesses thrive.
| Year Founded | 2021 |
| Founders | Garnet Heraman, William Crowder |
| Investment Stage | Early Stage, Seed |
| Nº of Investments | 15 (6 as Lead Investor) |
| Nº of Exits | — |
| Contact | press@aperturevc.com |
Focusing on the Mid-Atlantic region, Rittenhouse Ventures backs capital-efficient emerging technology companies with early-stage funding. They concentrate on small financing rounds for startups in sectors including healthcare IT, pharmaceutical IT, and financial technology.
| Year Founded | 2006 |
| Founders | Bruce Luehrs, Saul Richter |
| Investment Stage | Early Stage, Late Stage, Seed |
| Nº of Investments | 35 (16 as Lead Investor) |
| Nº of Exits | 13 (1 IPO'd) |
| Contact | saul@rittenhouse.vc / +1-215-972-1502 |
Built by students for students, Dorm Room Fund gives entrepreneurial undergrads and grad students their first $20,000 check. As a community powered by First Round, they connect founders with a strong network of investors and mentors to help launch their ventures.
| Year Founded | 2012 |
| Founders | An Nguyen, CeCe Cheng, Josh Kopelman, Phin Barnes |
| Investment Stage | Seed |
| Nº of Investments | 216 (7 as Lead Investor) |
| Nº of Exits | 33 (1 IPO'd) |
| Contact | info@dormroomfund.com / (215) 222-1085 |
Through its Greenhouse Fund, BioAdvance provides pre-seed and seed-stage capital to life sciences companies in Southeastern Pennsylvania. They support startups developing therapeutics, medical devices, and diagnostics to address major health problems like cancer, Alzheimer's disease, and neurological illnesses.
| Year Founded | 2003 |
| Founders | Barbara S. Schilberg, Gregory Harriman |
| Investment Stage | Early Stage, Late Stage, Seed |
| Nº of Investments | 181 (24 as Lead Investor) |
| Nº of Exits | 23 (7 IPO'd) |
| Contact | info@bioadvance.com / 610.230.0544 |
Ben Franklin Technology Partners of Southeastern Pennsylvania provides seed-stage capital to the region’s technology companies, aiming to create jobs and bolster the local economy. They also build crucial university and industry partnerships that help accelerate scientific discoveries from the lab to the commercial market.
| Year Founded | 1982 |
| Founders | — |
| Investment Stage | Early Stage, Grant, Seed |
| Nº of Investments | 232 (71 as Lead Investor) |
| Nº of Exits | 45 (3 IPO'd) |
| Contact | info@sep.benfranklin.org / 215.972.6700 |
Ground Up Ventures invests in pre-seed and seed stage startups across the United States and Israel, backing ambitious founders who are solving real-world problems. Their main advantage is a community of over 300 executives and founders that provides hands-on support to portfolio companies like Viz.ai and Guesty.
| Year Founded | 2017 |
| Founders | Cory Moelis, David Stark |
| Investment Stage | Early Stage, Seed |
| Nº of Investments | 49 (4 as Lead Investor) |
| Nº of Exits | 5 |
SRI Capital backs early-stage startups in India and the US, primarily focusing on enterprise software and deep tech applications for the American market. They also champion the Digital India movement by investing in local consumer products and adapting global innovations for the Indian middle class.
Red & Blue Ventures provides seed and early-stage funding to technology companies emerging from the University of Pennsylvania community. They specialize in backing founders with a Penn affiliation, helping them transform their ideas into viable businesses.
| Year Founded | 2016 |
| Founders | Brett Topche, David Bell, Michael Aronson |
| Investment Stage | Early Stage, Late Stage, Seed |
| Nº of Investments | 30 (3 as Lead Investor) |
| Nº of Exits | 4 |
| Contact | +1 610-639-8394 |