Maryland's startup ecosystem shows significant strength in sectors like clean energy, defense technology, and cybersecurity. These companies are spread throughout the state, from Rockville to Baltimore.
Clean energy developer X-energy leads with $1B in total funding. Other major players include autonomous systems firm Forterra and cybersecurity company Huntress, which have raised $411.3M and $309.8M respectively.
Below is our list of 35 Maryland startups worth keeping an eye on.
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Get the Sheet for $50X-energy develops advanced small modular nuclear reactors and proprietary fuel to provide clean, reliable energy. Their technology is designed to be a safer and more scalable alternative to traditional nuclear power plants.
| Year Founded | 2009 |
| Founders | Kam Ghaffarian |
| Funding Amount | $1B |
| Startup Size | Large Team (251-1,000) |
| Last Funding Status | Private Equity |
| Top Investors | Alumni Ventures, Ares Management, Jane Street Capital, University of Michigan, NGP Energy Capital Management |
Forterra develops autonomous systems for ground-based vehicles, focusing on defense and industrial applications. Their AutoDrive® platform is a vehicle-agnostic software kit that can be retrofitted onto existing vehicles for complex, off-road operations.
| Year Founded | 2002 |
| Founders | Alberto Lacaze, Karl Murphy |
| Funding Amount | $411.3M |
| Startup Size | Large Team (251-1,000) |
| Last Funding Status | Undisclosed |
| Top Investors | XYZ Venture Capital, Luminar, SoftBank Vision Fund, Crescent Cove Advisors, Enlightenment Capital |
Mytonomy builds healthcare cloud solutions focused on video-based patient education and engagement. Their platform enables providers to stream tailored video content, helping patients better understand their medical journey and treatment options.
| Year Founded | 2011 |
| Founders | Anjali Kataria, Vinay Bhargava |
| Funding Amount | $32M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | — |
| Top Investors | Level Equity Management, Kapor Capital, NewSchools Venture Fund, MedStar Health, Gokul Rajaram |
Huntress builds a managed security platform that combines automated detection software with a team of human threat analysts. They focus on delivering enterprise-grade cybersecurity to small and mid-sized businesses, a market often underserved by other security providers.
| Year Founded | 2015 |
| Founders | Chris Bisnett, John Ferrell, Kyle Hanslovan, Liz Kokoska |
| Funding Amount | $309.8M |
| Startup Size | Large Team (251-1,000) |
| Last Funding Status | Series D |
| Top Investors | Sapphire Ventures, JMI Equity, Kleiner Perkins, Forgepoint Capital, SaaS Ventures |
Employee Navigator builds an all-in-one software platform for benefits, HR, and compliance. Their SaaS solution is designed for insurance brokers and HR departments to manage everything from new hire onboarding to ACA reporting.
| Year Founded | 2008 |
| Founders | George Reese |
| Funding Amount | $134M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Secondary Market |
| Top Investors | JMI Equity, Spectrum Equity |
EcoMap Technologies creates AI-driven platforms that map and organize complex ecosystems such as industries and communities. Their technology makes information accessible by automatically centralizing resources and data into a single, navigable platform.
| Year Founded | 2018 |
| Founders | Anthony Caesar, Pava LaPere, Sherrod Davis |
| Funding Amount | $14.3M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Undisclosed |
| Top Investors | TEDCO, Techstars, Las Olas Venture Capital, Cofounders Capital, Conscious Venture Lab |
b.well Connected Health offers a digital health platform that unifies a person's complete medical history in one place. The technology aggregates records from various sources, including doctors, labs, and insurance plans, to give individuals a comprehensive view of their health data.
| Year Founded | 2015 |
| Founders | Bryan Jones, Kristen Valdes |
| Funding Amount | $118.8M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Debt Financing |
| Top Investors | Trinity Capital, Portfolia, Capital Factory, RTI International, Keiretsu Capital |
Quantum Xchange builds a crypto-agile key delivery system that makes an organization's transmitted data safe from quantum computing attacks. The company's Phio Trusted Xchange (TX) platform is designed to protect against "harvest now, decrypt later" threats by future-proofing existing encryption.
| Year Founded | 2018 |
| Founders | Hal Chapel |
| Funding Amount | $23.5M |
| Startup Size | Founding Team (1-10) |
| Last Funding Status | Series A |
| Top Investors | New Technology Ventures |
Scene Health tackles medication non-adherence through a program that combines personalized support with video technology. Their platform uses a method called video Directly Observed Therapy (DOT), helping patients with chronic and infectious diseases stick to their treatment plans.
| Year Founded | 2008 |
| Founders | Morad Elmi, Sebastian Seiguer, Sharon Kong |
| Funding Amount | $36.4M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Grant |
| Top Investors | Gaingels, TEDCO, Kapor Capital, National Institutes of Health, Sand Hill Angels |
InventWood creates a new class of advanced materials by transforming natural wood for high-performance applications. The company's portfolio includes products like MettleWood, a material stronger than steel, designed as a sustainable alternative for the manufacturing and construction industries.
| Year Founded | 2016 |
| Founders | Amy Gong |
| Funding Amount | $44M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Series A |
| Top Investors | Maryland Department of Commerce, US Department of Energy, Builders Vision, MUUS Climate Partners, Grantham Foundation |
25 Additional Maryland Startups Worth Following
Those top ten companies are just a small slice of what’s happening in Maryland right now. The state has a deep bench of startups in biotech and security, which together have raised more than $1.8 billion.
Some are just getting started while others have been growing for years. Here are the other companies that make Maryland's startup community so strong.