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Top 100 Therapeutics Startups to Watch in 2026

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The therapeutics sector is seeing major investment across many areas of health. Companies are tackling everything from cancer treatment to mental healthcare access.

For example, Avenzo Therapeutics has raised over $841 million for oncology since 2022. The field also includes companies like Midi Health, which focuses on virtual care for women.

Below is our list of 100 Therapeutics startups worth keeping an eye on.

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Odyssey Therapeutics creates precision medicines to treat patients with cancer and inflammatory diseases. Their discovery platform combines machine learning with deep expertise in biology and chemistry to develop novel immunomodulators and oncology drugs.

HeadquartersCambridge, Massachusetts, United States
Year Founded2021
FoundersDavid Pompliano, Gary Glick
Funding Amount$700M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries D
Top InvestorsTPG, General Catalyst, OrbiMed, Lightspeed Venture Partners, Catalio Capital Management

Midi Health built a virtual care platform to support women through menopause and other midlife health transitions. The service connects patients with trained clinicians who provide personalized treatment for hormonal changes and related conditions.

HeadquartersLos Angeles, California, United States
Year Founded2021
FoundersJoanna Strober, Sharon Meers
Funding Amount$152M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries C
Top InvestorsFelicis, GV, Muse Capital, Operator Collective, Emerson Collective

Enveda Biosciences develops novel medications by exploring the chemical compounds found in plants. Their drug discovery platform uses machine learning to identify promising molecules for new therapeutics.

HeadquartersBoulder, Colorado, United States
Year Founded2019
FoundersViswa Colluru
Funding Amount$529.9M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries D
Top InvestorsVillage Global, Lux Capital, Catalio Capital Management, Sanofi, FPV Ventures

Headway builds a mental healthcare system that makes it easier for patients to find a therapist who accepts their insurance. Their platform also helps providers by enabling them to accept insurance and scale their private practices.

HeadquartersNew York, New York, United States
Year Founded2019
FoundersAndrew Adams, Dan Ross, Jake Sussman, Kevin Chan
Funding Amount$325.5M
Startup SizeLarge Team (251-1,000)
Last Funding StatusSeries D
Top InvestorsAndreessen Horowitz, Accel, Forerunner, Thrive Capital, Bossa Invest

Avenzo Therapeutics develops targeted oncology therapies designed to treat various forms of cancer. The company focuses on advancing its clinical pipeline to provide new options for patients with unmet medical needs.

HeadquartersSan Diego, California, United States
Year Founded2022
FoundersAthena Countouriotis, Mohammad Hirmand
Funding Amount$841.9M
Startup SizeLean Team (11-50)
Last Funding StatusSeries B
Top InvestorsOrbiMed, New Enterprise Associates, INCE Capital, SR One, Lilly Asia Ventures

Character Biosciences built a platform that merges genomics, clinical data, and AI to find new ways to treat complex diseases. Their work currently focuses on Age-related Macular Degeneration (AMD), aiming to develop novel diagnostics and therapeutics for patients.

HeadquartersJersey City, New Jersey, United States
Year Founded2018
FoundersCheng Zhang, Marcel van der Brug
Funding Amount$137M
Startup SizeLean Team (11-50)
Last Funding StatusSeries B
Top InvestorsCatalio Capital Management, Industry Ventures, S32, Cantos, Casdin Capital

CHARM Therapeutics applies 3D deep learning to discover and develop novel small molecule medicines against difficult-to-drug targets. Their proprietary platform, DragonFold, powers a lead program in oncology that targets a key protein interaction driving acute leukemias.

HeadquartersLondon, England, United Kingdom
Year Founded2021
FoundersDavid Baker, Laksh Aithani
Funding Amount$162.7M
Startup SizeLean Team (11-50)
Last Funding StatusSeries B
Top InvestorsGeneral Catalyst, OrbiMed, NVIDIA, Khosla Ventures, New Enterprise Associates

SetPoint Medical develops a bioelectronic medicine platform to treat chronic autoimmune diseases. Their proprietary device stimulates the vagus nerve, offering a new therapeutic approach for conditions like rheumatoid arthritis as an alternative to drug therapy.

HeadquartersValencia, California, United States
Year Founded2007
FoundersJim Broderick, Kevin Tracey, Shaw Warren
Funding Amount$496.4M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries D
Top InvestorsNorwest Venture Partners, New Enterprise Associates, Catalio Capital Management, Boston Scientific, Elevage Medical Technologies

Grow Therapy created a mental health marketplace that connects patients with therapists who match their needs and insurance. The platform empowers therapists by handling administrative tasks like booking and billing, allowing them to launch and grow their own private practices.

HeadquartersNew York, New York, United States
Year Founded2020
FoundersAlan Ni, Jake Cooper, Manoj Kanagaraj
Funding Amount$178M
Startup SizeLarge Team (251-1,000)
Last Funding StatusSeries C
Top InvestorsVillage Global, Sequoia Capital, Goldman Sachs, TCV, Transformation Capital

Massive Bio built an AI-powered platform to connect cancer patients with personalized clinical trial options. Their service helps patients access advanced treatments while allowing pharmaceutical companies to more easily find participants for oncology research.

HeadquartersNew York, New York, United States
Year Founded2015
FoundersArturo Loaiza-Bonilla, Cagatay Culcuoglu, Selin Kurnaz
Funding Amount$23.8M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries B
Top Investors500 Global, Revo Capital, 500 Emerging Europe, Princeton Alumni Angels, ImpactAssets

90 Additional Therapeutics Startups Worth Following

Those top 10 companies are just a small slice of what’s happening in the field. A huge number of new startups are focused on biotech and AI to develop new treatments.

In total, the companies on our list have raised over $15 billion, showing a big vote of confidence from investors. Here’s a look at the other startups that are pushing the industry forward.

StartupMain IndustryYear FoundedAmount RaisedLast Funding Round
Sparrow Pharmaceuticals logo Sparrow PharmaceuticalsBiotech2013$156.3MSeries B
Galvanize Therapeutics logo Galvanize TherapeuticsHealthcare2015$248.5MSeries C
Skyhawk Therapeutics logo Skyhawk TherapeuticsBiotech2016$181.2MVenture Round
Star Therapeutics logo Star TherapeuticsHealthcare2018$315MSeries D
Sword Health logo Sword HealthAI2015$493.5MVenture Round
Cellares logo CellaresBiotech2019$355MSeries C
Mercy BioAnalytics logo Mercy BioAnalyticsBiotech2018$127.3MSeries B
Ensoma logo EnsomaBiotech2019$258MVenture Round
Presence logo PresenceEducation2009$414.2MPrivate Equity
Strand Therapeutics logo Strand TherapeuticsBiotech2017$257.2MSeries B
Enlaza Therapeutics logo Enlaza TherapeuticsBiotech2020$180MVenture Round
Seed Health logo Seed HealthBiotech2016$40MSeries A
Predicta Biosciences logo Predicta BiosciencesBiotech2023$28.6MSeries A
Elektrofi logo ElektrofiHealthcare2016$154.1MSeries C
Retro Biosciences logo Retro BiosciencesBiotech2021$180MAngel
Iambic logo IambicAI2019$203MSeries B
Scribe Therapeutics logo Scribe TherapeuticsBiotech2017$120MConvertible Note
Wugen logo WugenBiotech2018$287MSeries C
Tahoe Therapeutics logo Tahoe TherapeuticsAI2022$42MSeries A
Opus Genetics logo Opus GeneticsBiotech2004$22.7MGrant
HAYA Therapeutics logo HAYA TherapeuticsBiotech2017$1.1BGrant
Click Therapeutics logo Click TherapeuticsBiotech2012$1BSeries C
Orbital Therapeutics logo Orbital TherapeuticsHealthcare2022$270MSeries A
Replicate Bioscience logo Replicate BioscienceBiotech2020$46MSeries A
Leal Therapeutics logo Leal TherapeuticsHealthcare2021$75MSeries A
Dewpoint Therapeutics logo Dewpoint TherapeuticsBiotech2018$346.1MSeries D
Interius BioTherapeutics logo Interius BioTherapeuticsBiotech2019$175.9MUndisclosed
INBRAIN Neuroelectronics logo INBRAIN NeuroelectronicsBiotech2020$119.8MGrant
Swing Therapeutics logo Swing TherapeuticsBiotech2019$34MUndisclosed
Centivax logo CentivaxBiotech2020$59.2MSeries A
Epigenic Therapeutics logo Epigenic TherapeuticsBiotech2021$122MSeries B
PhaseV logo PhaseVAI2023$65MSeries A
Blueprint logo BlueprintAI2019$32.3MVenture Round
Circle Pharma logo Circle PharmaBiotech2012$207.5MSeries D
Boulder Care logo Boulder CareHealthcare2017$85.2MSeries C
Alcyone Therapeutics logo Alcyone TherapeuticsBiotech2010$23MCorporate Round
Prellis Biologics logo Prellis BiologicsManufacturing2016$79.4MSeries C
Noctrix Health logo Noctrix HealthHealthcare2018$90.5MVenture Round
Leyden Labs logo Leyden LabsBiotech2020$315.2MVenture Round
Spark Biomedical logo Spark BiomedicalHealthcare2018$32.8MGrant
Maxion Therapeutics logo Maxion TherapeuticsHealthcare2020£73MSeries A
C2N Diagnostics logo C2N DiagnosticsBiotech2007$85.7MCorporate Round
NextRNA Therapeutics logo NextRNA TherapeuticsBiotech2020$56.1MSeries A
Dispatch Bio logo Dispatch BioBiotech2022$216MSeries A
Crystalys Therapeutics logo Crystalys TherapeuticsBiotech2025$205MSeries A
Sonoma Biotherapeutics logo Sonoma BiotherapeuticsBiotech2020$365MCorporate Round
Atavistik Bio logo Atavistik BioBiotech2021$100MVenture Round
Orna Therapeutics logo Orna TherapeuticsBiotech2019$321MSeries B
Seed Therapeutics logo Seed TherapeuticsBiotech2019$30MSeries A
Atsena Therapeutics logo Atsena TherapeuticsBiotech2019$237.6MSeries C
Slingshot Biosciences logo Slingshot BiosciencesBiotech2012$64.2MSeries A
Pretzel Therapeutics logo Pretzel TherapeuticsBiotech2019$72.5MVenture Round
Xaira Therapeutics logo Xaira TherapeuticsAI2023$1BSeries A
Incyclix Bio logo Incyclix BioBiotech2020$47.2MSeries B
Brightside Health logo Brightside HealthHealthcare2017$114.4MSeries C
BigHat Biosciences logo BigHat BiosciencesAI2019$99.3MSeries B
Woebot Health logo Woebot HealthAI2017$123.3MVenture Round
Remedium Bio logo Remedium BioBiotech2020$2.3MCorporate Round
Nusano logo NusanoBiotech2013$115MSeries C
Polaris Genomics logo Polaris GenomicsBiotech2017$5.6MDebt Financing
Vida Health logo Vida HealthHealthcare2014$216.5MVenture Round
BioTissue logo BioTissueBiotech2001$110MSeries C
MOMA Therapeutics logo MOMA TherapeuticsBiotech2020$236MSeries B
Insitro logo InsitroBiotech2018$643MSeries C
SonderMind logo SonderMindHealthcare2014$183MSeries C
Cellvie logo CellvieBiotech2018$15.5MSeed
1910 Genetics logo 1910 GeneticsAI2018$26.7MVenture Round
GT Medical Technologies logo GT Medical TechnologiesHealthcare2017$162.5MSeries D
Mabylon logo MabylonBiotech2015CHF31.3MConvertible Note
Pathos logo PathosAI2020$447MSeries D
SpectrumAi logo SpectrumAiSports2021$29MSeries A
Candid Therapeutics logo Candid TherapeuticsBiotech2024$370MSeries A
Nutcracker Therapeutics logo Nutcracker TherapeuticsBiotech2018$241MSeries C
SK biopharmaceuticals logo SK biopharmaceuticalsBiotech2011$180MGrant
Envisagenics logo EnvisagenicsAI2014$52.1MSeries B
Ashvattha Therapeutics logo Ashvattha TherapeuticsBiotech2015$148MSeries B
Judo Bio logo Judo BioBiotech2021$100MSeries A
Draig Therapeutics logo Draig TherapeuticsBiotech2024$140MSeries A
Epitopea logo EpitopeaBiotech2021$44.8MSeed
Capstan Therapeutics logo Capstan TherapeuticsBiotech2021$340MSeries B
Saluda Medical logo Saluda MedicalHealthcare2010$499.5MVenture Round
AbsoluteCARE logo AbsoluteCAREHealthcare2000$252MPrivate Equity
Allay Therapeutics logo Allay TherapeuticsBiotech2017$149.5MSeries D
ResBiotic logo ResBioticBiotech2018$16.1MSeries A
Ansa Biotechnologies logo Ansa BiotechnologiesBiotech2018$128.6MSeries B
Nuvig Therapeutics logo Nuvig TherapeuticsBiotech2021$208MSeries B
Alltrna logo AlltrnaBiotech2018$159MSeries B
BlossomHill Therapeutics logo BlossomHill TherapeuticsBiotech2020$173MSeries B
Cartwheel logo CartwheelHealthcare2022$55.2MSeries B
Talus Bio logo Talus BioAI2020$27.8MSeed

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