Both Cambridge (Massachusetts) and Cambridge (UK) are a center for startups focused on deep technology and life sciences. Both areas are particularly known for its concentration of artificial intelligence and biotechnology companies.
Among them, Commonwealth Fusion Systems has raised $2.9 billion to develop commercial fusion energy. Companies like Odyssey Therapeutics and AI music creator Suno have also received hundreds of millions in funding.
Below is our list of 93 Cambridge startups worth keeping an eye on.
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Get the Sheet for $50CuspAI is building an AI platform to design and discover new materials from the molecular level. Their technology is focused on accelerating solutions for global challenges, particularly in carbon capture and sustainable product development.
| Year Founded | 2024 |
| Founders | Alyn Chad Edwards, Chad Edwards, Max Welling |
| Funding Amount | $130M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Series A |
| Top Investors | Temasek Holdings, Lightspeed Venture Partners, Samsung Electronics, Northzone, LocalGlobe |
Commonwealth Fusion Systems designs and develops commercial fusion energy systems to produce clean, limitless energy. Their work focuses on using powerful, high-temperature superconducting magnets to build compact and commercially viable fusion power plants.
| Year Founded | 2017 |
| Founders | Dan Brunner, Martin Greenwald, Robert Mumgaard |
| Funding Amount | $2.9B |
| Startup Size | Major Organization (1,001-5,000) |
| Last Funding Status | Series B |
| Top Investors | Temasek Holdings, Khosla Ventures, HOF Capital, Quiet Capital, Google |
OpenEvidence builds an AI-powered platform for medical search and clinical decision support. Their tool helps clinicians and researchers get quick answers to complex questions, complete with citations from medical literature.
| Year Founded | 2021 |
| Founders | Daniel Nadler, Zachary Ziegler |
| Funding Amount | $317M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Series B |
| Top Investors | Sequoia Capital, Coatue, Conviction, Thrive Capital, Kleiner Perkins |
Suno builds AI technology that empowers anyone to create original music from text prompts. Their web-based tool can generate complete songs, including vocals and instrumentation, making music creation accessible to people without a musical background.
| Year Founded | 2022 |
| Founders | Georg Kucsko, Keenan Freyberg, Martin Camacho, Mikey Shulman |
| Funding Amount | $375M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Series C |
| Top Investors | Menlo Ventures, Lightspeed Venture Partners, Founder Collective, Matrix, Daniel Gross, Scott Belsky |
Odyssey Therapeutics develops precision immunomodulators and oncology medicines for patients with cancer and inflammatory diseases. Their drug discovery platform is engineered to address some of the most complex targets in immunology.
| Year Founded | 2021 |
| Founders | David Pompliano, Gary Glick |
| Funding Amount | $700M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series D |
| Top Investors | TPG, General Catalyst, OrbiMed, Lightspeed Venture Partners, Catalio Capital Management |
Liquid AI develops efficient, general-purpose artificial intelligence systems designed to operate at any scale. Their core technology is a new class of AI models that are more dynamic and adaptable than traditional neural networks.
| Year Founded | 2023 |
| Founders | Alexander Amini, Daniela Rus, Mathias Lechner, Ramin Hasani |
| Funding Amount | $293.2M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series A |
| Top Investors | Automattic, Safar Partners, Samsung NEXT, Isai, Bold Capital Partners |
Lila Sciences creates a scientific superintelligence platform to accelerate discovery in complex fields. Their system powers autonomous labs for advanced research in life sciences, chemistry, and materials science.
| Year Founded | 2023 |
| Founders | Molly Gibson, Noubar Afeyan |
| Funding Amount | $435M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series A |
| Top Investors | Collective Global Management, The Mathers Foundation, General Catalyst, Alumni Ventures, Abu Dhabi Investment Authority |
Ketryx develops an AI-driven compliance platform that automates documentation tasks for regulated product teams. Their software helps companies in sectors like medical devices and life sciences streamline complex workflows and accelerate their time to market.
| Year Founded | 2021 |
| Founders | Erez Kaminski, Jan Pöschko |
| Funding Amount | $57M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series B |
| Top Investors | Lightspeed Venture Partners, Transformation Capital, 53 Stations, E14 Fund, Ubiquity Ventures |
Solo.io delivers cloud-native application networking solutions built on open-source technologies like Istio and Envoy. Their platform provides API gateway and service mesh tools that help companies connect, secure, and observe their applications across any environment.
| Year Founded | 2017 |
| Founders | Idit Levine |
| Funding Amount | $171.5M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series C |
| Top Investors | Quiet Capital, True Ventures, Redpoint, Haystack, Altimeter Capital |
Insilico Medicine develops a proprietary AI platform designed to accelerate the discovery and development of new drugs. They use this system to create novel therapeutics for cancer and other age-related diseases.
| Year Founded | 2014 |
| Founders | Alex Zhavoronkov |
| Funding Amount | $624.3M |
| Startup Size | Large Team (251-1,000) |
| Last Funding Status | Series E |
| Top Investors | OrbiMed, HSG, B Capital, Eli Lilly, Qiming Venture Partners |
83 Additional Cambridge Startups Worth Following
Our top ten picks offer a glimpse into the exciting work happening in Cambridge. Across both cities, founders in fields like biotech and AI have raised billions to bring their ideas to life.
Some of these companies are just starting out, while others are growing quickly. Here’s a look at the other startups shaping both Cambridge startup ecosystem.
