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Top 77 Chemical Startups to Watch in 2026

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The chemical industry is seeing new companies tackle big problems like sustainability and material science. These startups are developing new ways to create everything from batteries to cement.

Group14 Technologies has raised $1.2B for its advanced battery technology. Another company, CuspAI, was founded in 2024 and has already secured $130M to use AI for material discovery.

Below is our list of 77 Chemical startups worth keeping an eye on.

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CuspAI is building a platform that uses generative AI to design and discover new materials for a wide range of applications. Their technology focuses on creating materials that can help solve major global challenges, including carbon capture and storage.

HeadquartersCambridge, Cambridgeshire, United Kingdom
Year Founded2024
FoundersAlyn Chad Edwards, Chad Edwards, Max Welling
Funding Amount$130M
Startup SizeLean Team (11-50)
Last Funding StatusSeries A
Top InvestorsTemasek Holdings, Lightspeed Venture Partners, Samsung Electronics, Northzone, LocalGlobe

Group14 Technologies manufactures advanced silicon battery technology that serves as a drop-in replacement for graphite anodes. Their silicon-carbon composite material helps manufacturers create more powerful and faster-charging lithium-ion batteries for electric vehicles and consumer electronics.

HeadquartersWoodinville, Washington, United States
Year Founded2015
FoundersAaron Feaver, Rick Costantino, Rick Luebbe
Funding Amount$1.2B
Startup SizeLarge Team (251-1,000)
Last Funding StatusSeries D
Top InvestorsLightrock, OMERS Ventures, Yaletown Partners, Decarbonization Partners, Vsquared Ventures

Arzeda designs and manufactures custom proteins and enzymes for use in pharmaceuticals and industrial chemicals. Their work is powered by an AI and machine learning platform that enables the creation of novel biological components.

HeadquartersSeattle, Washington, United States
Year Founded2009
FoundersAlexandre Zanghellini, Daniela Grabs, David Baker, Eric Althoff
Funding Amount$108.1M
Startup SizeMid-Size Team (51-250)
Last Funding StatusGrant
Top InvestorsNational Science Foundation, Casdin Capital, Sofinnova Partners, Universal Materials Incubator, Circulate Capital

OXCCU tackles industrial emissions by converting captured carbon dioxide and hydrogen into useful materials. Their technology produces sustainable aviation fuels, chemicals, and biodegradable plastics, offering a new decarbonization pathway for hard-to-abate industries.

HeadquartersOxford, Oxfordshire, United Kingdom
Year Founded2021
FoundersAndrew Symes, Benzhen Yao, Jane Jin, Peter Edward, Tiancun Xiao
Funding Amount$54.1M
Startup SizeFounding Team (1-10)
Last Funding StatusSeries B
Top InvestorsAramco Ventures, Trafigura, Clean Energy Ventures, Hostplus, IP Group

Nitricity creates nitrogen fertilizer using a process powered by only air, water, and renewable energy. Their technology provides a climate-friendly fertilizer for farmers, helping to decarbonize a critical part of the agricultural supply chain.

HeadquartersFremont, California, United States
Year Founded2018
FoundersJay Schwalbe, Joshua McEnaney, Nicolas Pinkowski
Funding Amount$90.9M
Startup SizeLean Team (11-50)
Last Funding StatusSeries B
Top InvestorsNational Science Foundation, Alumni Ventures, Khosla Ventures, Lowercarbon Capital, Bossa Invest

Cylib developed a proprietary recycling process for end-of-life batteries and production scrap. Their technology transforms this waste into marketable raw materials, helping to build a circular economy for the battery industry.

HeadquartersAachen, Nordrhein-Westfalen, Germany
Year Founded2022
Founders
Funding Amount$92.7M
Startup SizeLean Team (11-50)
Last Funding StatusGrant
Top InvestorsSpeedinvest, 10x Founders, Bosch Ventures, Vsquared Ventures, Porsche Ventures

Vantage Specialty Chemicals creates specialty ingredients derived from natural sources for the personal care and industrial markets. Their portfolio of chemicals provides the building blocks for products ranging from cosmetics to industrial lubricants.

HeadquartersChicago, Illinois, United States
Year Founded2008
Founders
Funding Amount$900M
Startup SizeLarge Team (251-1,000)
Last Funding StatusDebt Financing
Top InvestorsApollo, Silver Point Capital, L.P.

Twelve has developed a carbon transformation technology that converts captured CO₂ into essential products. Their process creates sustainable alternatives to fossil fuels, including chemicals and aviation fuel, directly from the air.

HeadquartersBerkeley, California, United States
Year Founded2015
FoundersEtosha Cave, Kendra Kuhl, Nicholas Flanders
Funding Amount$929.4M
Startup SizeLarge Team (251-1,000)
Last Funding StatusVenture Round
Top InvestorsNational Science Foundation, TPG, Techstars, Greycroft, Global Brain Corporation

FREDsense develops portable field kits that allow industries to quickly analyze water quality on-site. Their sensor technology provides rapid, lab-grade results directly to the people who need them, bypassing traditional laboratory wait times.

HeadquartersCalgary, Alberta, Canada
Year Founded2014
FoundersDavid Lloyd, Emily Hicks, Iain George, Lisa Oberding, Robert Mayall
Funding Amount$10M
Startup SizeLean Team (11-50)
Last Funding StatusSeries A
Top InvestorsElemental Impact, Emerald Technology Ventures, Creative Destruction Lab (CDL), FundersClub, Accelerate Fund

Fortera produces zero CO₂ cement for the construction industry through its proprietary ReCarb process. This system captures emissions directly from cement plants and mineralizes the CO₂ into a ready-to-use cementitious material.

HeadquartersSan Jose, California, United States
Year Founded2007
FoundersMichael Weiss, Ryan Gilliam, Samir Kaul
Funding Amount$175.5M
Startup SizeMid-Size Team (51-250)
Last Funding StatusVenture Round
Top InvestorsTemasek Holdings, Alumni Ventures, Khosla Ventures, Hercules Capital, Wollemi

67 Additional Chemical Startups Worth Following

Those top 10 companies are a great snapshot, but there's a much bigger picture. Together, the startups below have raised billions to tackle challenges in manufacturing, biotech, and climate.

Some are new and scrappy, while others are already scaling up fast. Here is a look at the other chemical startups to keep an eye on.

StartupMain IndustryYear FoundedAmount RaisedLast Funding Round
BIOWEG logo BIOWEGManufacturing2019$29.6MSeries A
Distil logo DistilManufacturing2023$10.8MSeries A
enadyne logo enadyneManufacturing2022$7MSeed
EnergyX logo EnergyXManufacturing2018$649.5MEquity Crowdfunding
Nova Chemicals logo Nova ChemicalsManufacturing1954$883.4MGrant
Azelis logo AzelisManufacturing2001CA$600MDebt Financing
Lithium de france logo Lithium de franceManufacturing2020$84MSeries B
Albert Invent logo Albert InventManufacturing2022$50MVenture Round
Drug Hunter logo Drug HunterBiotech2018$6.3MSeed
DePoly logo DePolyManufacturing2020$41.1MSeed
NextChem logo NextChemEnvironment2018$187.5MDebt Financing
Evolved By Nature logo Evolved By NatureBiotech2013$190MSeries C
Greenitio logo GreenitioEnterprise2021$1.5MSeed
Altris logo AltrisHardware2017$32MSeries B
Again logo AgainBiotech2020$98.8MSeries A
Scimplify logo ScimplifyManufacturing2023$53.2MSeries B
INERATEC logo INERATECManufacturing2014€208MGrant
Nanosci logo NanosciManufacturing2020$1.2MSeed
Gujarat Fluorochemicals logo Gujarat FluorochemicalsManufacturing1987₹10BPrivate Equity
Greenlyte Carbon Technologies logo Greenlyte Carbon TechnologiesEnvironment2022€18.5M
Crystal Crop Protection logo Crystal Crop ProtectionAgTech1994₹4.5BVenture Round
Anaphite logo AnaphiteManufacturing2018£19.3MSeries A
C-Capture logo C-CaptureManufacturing2009£26.7MVenture Round
Draslovka logo DraslovkaManufacturing1906$150MPrivate Equity
ICODOS logo ICODOSManufacturing2022€2MPre-Seed
Nero Materials logo Nero MaterialsManufacturing2024€1.1MGrant
Zhongke Guosheng logo Zhongke GuoshengManufacturing2021CN¥460MSeries A
CarbonScape logo CarbonScapeManufacturing2008$18.3MGrant
EQUATE Petrochemical Company logo EQUATE Petrochemical CompanyManufacturing1995$750MDebt Financing
Nintx logo NintxBiotech2021$15MSeries A
Nuada logo NuadaEnvironment2012£12.2MGrant
NitroCapt logo NitroCaptAgTech2014€5.9MVenture Round
Be8 logo Be8Manufacturing2005R$250MDebt Financing
Ganext logo GanextManufacturing2020CN¥200MSeries B
TripleW Group NV logo TripleW Group NVBiotech2016$43.8MGrant
ChemInnovation logo ChemInnovationAI2023€1.7MGrant
HQS Quantum Simulations logo HQS Quantum SimulationsManufacturing2017€14.3MSeed
Cyclize logo CyclizeManufacturing2023€4.8MSeed
NorcSi GmbH logo NorcSi GmbHHardware2020$10.7MVenture Round
Ioniqa Technologies logo Ioniqa TechnologiesManufacturing2009$42.5MCorporate Round
Chromologics logo ChromologicsBiotech2017$13MSeed
Gr3n Recycling logo Gr3n RecyclingManufacturing2013$10.1MGrant
Universallab logo UniversallabManufacturing2022$400kPre-Seed
Jolt Electrodes logo Jolt ElectrodesManufacturing2022$6MSeries A
Fujian Deer Technology logo Fujian Deer TechnologyManufacturing2014CN¥3.2BVenture Round
Rabigh Arabian Water & Electricity Company logo Rabigh Arabian Water & Electricity CompanyManufacturing2005SAR844MSecondary Market
Liverpool ChiroChem logo Liverpool ChiroChemBiotech2014£5.8MVenture Round
Kerionics logo KerionicsManufacturing2014€13.1MVenture Round
Carbometrics logo CarbometricsBiotech2018€2.1MVenture Round
Catalyco logo CatalycoManufacturing2018€1.9MGrant
Gaia Tech logo Gaia TechAgTech2021CHF665kPre-Seed
Apeiron Synthesis logo Apeiron SynthesisManufacturing2009€4.8MSeed
OPTITRADE logo OPTITRADEAgTech2024$15.1MDebt Financing
ReCatalyst logo ReCatalystManufacturing2021€1.7MSeed
Preventio logo PreventioAI2021€1.4MPre-Seed
Bioforany logo BioforanyBiotech2014CN¥50MSeed
ChemiTek logo ChemiTekManufacturing2018$1.8MSeed
Nanup logo NanupManufacturing2006CN¥200MSeries B
Raykol logo RaykolManufacturing2018CN¥100MSeries A
FIS Chemicals LTD logo FIS Chemicals LTDManufacturing1980£3.7MDebt Financing
Gekko Photonics logo Gekko PhotonicsManufacturing2019€1.9MAngel
Innoscentia logo InnoscentiaManufacturing2015€500kUndisclosed
Seram Coatings logo Seram CoatingsManufacturing2014$4.2MGrant
Evonik logo EvonikManufacturing2007
BASF Coatings logo BASF CoatingsManufacturing1972
ReLaDe logo ReLaDeManufacturing2016€50kGrant
Biosynth logo BiosynthManufacturing1966
Master Builders Solutions logo Master Builders SolutionsManufacturing1909
Hygear logo HygearManufacturing2002
TIB Chemicals logo TIB ChemicalsEnterprise1872
Westfalen logo WestfalenManufacturing1923
Compo GmbH logo Compo GmbHManufacturing1956
COMPO Expert GmbH logo COMPO Expert GmbHManufacturing1956
ServiBaños logo ServiBañosManufacturing

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