Colorado's startup ecosystem shows a strong presence in deep tech alongside various software sectors. The state is home to companies focused on quantum computing, aerospace, and data infrastructure.
This landscape includes heavily funded players like Vantage Data Centers, which has raised $33.6 billion. Other notable companies are Sierra Space, with $1.7 billion for its commercial space efforts, and the quantum computing firm Quantinuum.
Below is our list of 74 Colorado startups worth keeping an eye on.
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Get the Sheet for $50Quantinuum builds integrated quantum computers, developing both the hardware and the software to solve complex problems. Their technology accelerates the development of applications across critical fields like chemistry, cybersecurity, and finance.
| Year Founded | 2021 |
| Founders | Ilyas Khan |
| Funding Amount | $925M |
| Startup Size | Large Team (251-1,000) |
| Last Funding Status | Series B |
| Top Investors | QED Investors, JP Morgan Chase, NVentures, Amgen, Korea Investment Partners |
Vantage Data Centers develops and operates hyperscale data center campuses for the world’s leading cloud providers and AI enterprises. They provide the critical infrastructure that powers, cools, and protects the technology used by these large-scale businesses.
| Year Founded | 2010 |
| Founders | Jim Trout |
| Funding Amount | $33.6B |
| Startup Size | Major Organization (1,001-5,000) |
| Last Funding Status | Private Equity |
| Top Investors | Schroders Capital, La Caisse, Wells Fargo, Societe Generale, Ares Management |
Infleqtion develops software-configured, quantum-enabled products that range from high-precision sensors to full computing systems. Their technology is designed to power advancements in fields like secure communications, signal processing, and quantum information.
| Year Founded | 2007 |
| Founders | Dana Anderson, Jakob Reichel, Rainer Kunz, Theodor Hänsch |
| Funding Amount | $307.8M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series C |
| Top Investors | S32, Maverick Ventures, Foundry Group, U.S. Department of Defense, US Department of Energy |
Enveda Biosciences builds a drug discovery platform that finds novel medicines from plants. They use machine learning to map the chemistry of the natural world and identify promising drug candidates.
| Year Founded | 2019 |
| Founders | Viswa Colluru |
| Funding Amount | $529.9M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series D |
| Top Investors | Village Global, Lux Capital, Catalio Capital Management, Sanofi, FPV Ventures |
Sierra Space develops the foundational infrastructure for a commercial economy in low Earth orbit. Their key projects include the Dream Chaser spaceplane for cargo and crew transport and the LIFE habitat for in-space destinations.
| Year Founded | 2021 |
| Founders | Eren Ozmen, Fatih Ozmen |
| Funding Amount | $1.7B |
| Startup Size | Major Organization (1,001-5,000) |
| Last Funding Status | Series B |
| Top Investors | General Atlantic, Coatue, AE Industrial Partners, MUFG Bank, BlackRock Private Equity Partners |
Interlune develops technology to harvest natural resources, like Helium-3, from the Moon. They are working to establish a reliable supply of these materials for commercial markets on Earth.
| Year Founded | 2020 |
| Founders | Gary Lai, Indra Hornsby, Rob Meyerson |
| Funding Amount | $22.6M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Grant |
| Top Investors | Gaingels, Seven Seven Six, Liquid 2 Ventures, Shasta Ventures, US Department of Energy |
BillingPlatform offers a cloud-based platform that helps businesses automate their billing and revenue management processes. The software is designed to handle the complete quote-to-cash lifecycle, supporting everything from simple subscriptions to complex usage-based pricing models.
| Year Founded | 2012 |
| Founders | Leonid Solomonik, Nathan Shinn |
| Funding Amount | $104M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Private Equity |
| Top Investors | FTV Capital, Columbia Capital, Future Now Ventures |
Tilt builds a platform that helps companies manage the complexities of employee leave. Their software is designed to bring empathy and efficiency to the process, saving HR teams over 20 hours per leave.
| Year Founded | 2017 |
| Founders | Jennifer Henderson |
| Funding Amount | $33.5M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series B |
| Top Investors | Techstars, Matchstick Ventures, Origin Ventures, HearstLab, Rockies Venture Club |
Conga offers a suite of solutions that streamlines and automates critical business operations, from document generation to contract management. Their integrated platform helps teams across sales, legal, and operations manage the entire commercial process, from initial quotes to final contract renewals.
| Year Founded | 2006 |
| Founders | Mark Whiteside, Michael E. Markham |
| Funding Amount | $117M |
| Startup Size | Major Organization (1,001-5,000) |
| Last Funding Status | Venture Round |
| Top Investors | Insight Partners, Salesforce Ventures |
Gloo builds a technology platform designed to connect the entire faith ecosystem. Their tools help churches and faith-based groups reach new people and foster personal growth through deeper community relationships.
| Year Founded | 2012 |
| Founders | Scott Beck, Theresa Beck |
| Funding Amount | $151.6M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Undisclosed |
| Top Investors | — |
64 Additional Colorado Startups Worth Following
Our top ten picks are just a fraction of the companies building exciting things in Colorado. Many are focused on big fields like AI and energy, and together they have raised over $35 billion.
You'll find companies just getting started alongside others that are already growing quickly. Here’s a look at the rest of the startups shaping the Colorado startup ecosystem.
