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Top 100 San Francisco Startups to Watch in 2026

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San Francisco remains a key hub for technology startups, showing a clear concentration in artificial intelligence. The area is home to both long standing tech companies and a fresh crop of new ventures.

Industry leaders like OpenAI have raised funding as high as $78 billion. Other major players include Anthropic, which has secured $33.7 billion, and the payment processor Stripe.

Below is our list of 100 San Francisco startups worth keeping an eye on.

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Anthropic develops powerful and reliable AI models with a focus on safety and research. Their most well-known creation is Claude, a family of models used for everything from sophisticated dialogue to complex content creation.

Year Founded2021
FoundersDaniela Amodei, Dario Amodei, Jack Clark, Jared Kaplan, Sam McCandlish, Tom Brown
Funding Amount$33.7B
Startup SizeMajor Organization (1,001-5,000)
Last Funding StatusSeries F
Top InvestorsMenlo Ventures, TPG, General Catalyst, BlackRock, Insight Partners

Perplexity built an AI answer engine to provide direct, conversational answers to user questions. Their platform combines large language models with real-time search to deliver accurate, up-to-date information complete with source citations.

Year Founded2022
FoundersAndy Konwinski, Aravind Srinivas, Denis Yarats, Johnny Ho
Funding Amount$1.5B
Startup SizeMid-Size Team (51-250)
Last Funding StatusVenture Round
Top InvestorsNVIDIA, Accel, Bessemer Venture Partners, New Enterprise Associates, IVP

OpenAI develops advanced AI models, including the popular conversational tool ChatGPT. The AI research and deployment company aims to ensure that artificial general intelligence benefits all of humanity.

Year Founded2015
FoundersAndrej Karpathy, Durk Kingma, Elon Musk, Greg Brockman, Ilya Sutskever, John Schulman, Pamela Vagata, Sam Altman, Trevor Blackwell, Vicki Cheung, Wojciech Zaremba
Funding Amount$78B
Startup SizeMajor Organization (1,001-5,000)
Last Funding StatusVenture Round
Top InvestorsAndreessen Horowitz, TPG, NVIDIA, Citi, Khosla Ventures

Stripe builds a suite of APIs that power online payment processing for internet businesses of all sizes. Their platform provides the financial infrastructure for companies to manage revenue, prevent fraud, and expand internationally.

Year Founded2010
FoundersJohn Collison
Funding Amount$9.4B
Startup SizeEnterprise Organization (5,001+)
Last Funding StatusSecondary Market
Top InvestorsAndreessen Horowitz, General Catalyst, Temasek Holdings, Khosla Ventures, Sequoia Capital

Anysphere operates as an applied research lab developing AI solutions like Cursor to automate the process of writing code. Their tools are designed to help software engineers build and manage applications more efficiently.

Year Founded2022
FoundersAman Sanger, Arvid Lunnemark, Michael Truell, Sualeh Asif
Funding Amount$3.4B
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries D
Top InvestorsAndreessen Horowitz, Accel, Google, NVIDIA, Benchmark, Thrive Capital, DST Global

Cognition has developed Devin, the first AI software engineer capable of handling complex engineering tasks from start to finish. The applied AI lab focuses on building AI teammates that can reason and write code autonomously.

Year Founded2023
FoundersScott Wu, Steven Hao, Walden Yan
Funding Amount$896M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries C
Top InvestorsPear VC, South Park Commons, Khosla Ventures, 8VC, Lux Capital

Harness builds a software delivery platform that helps engineering and DevOps teams release applications into production. Their Continuous Delivery-as-a-Service solution automates the software lifecycle, allowing teams to ship code faster and more securely.

Year Founded2017
FoundersJyoti Bansal, Rishi Singh, Rishi Singh
Funding Amount$575M
Startup SizeMajor Organization (1,001-5,000)
Last Funding StatusDebt Financing
Top InvestorsNorwest Venture Partners, Gaingels, Menlo Ventures, Battery Ventures, IVP

Databricks developed a unified platform for data and AI that combines the features of data warehouses and data lakes. This lakehouse architecture allows data teams to collaborate on everything from business intelligence to machine learning projects in one place.

Year Founded2013
FoundersAli Ghodsi, Andy Konwinski, Arsalan Tavakoli-Shiraji, Ion Stoica, Matei Zaharia, Patrick Wendell, Reynold Xin
Funding Amount$21.8B
Startup SizeEnterprise Organization (5,001+)
Last Funding StatusVenture Round
Top InvestorsFranklin Templeton, Andreessen Horowitz, NVIDIA, Temasek Holdings, Gaingels

Writer has built a full-stack generative AI platform that helps large organizations scale their content creation. The platform ensures all written material, from marketing copy to internal documents, remains secure and consistent with the company's unique brand voice.

Year Founded2020
FoundersMay Habib, Waseem AlShikh
Funding Amount$326M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries C
Top InvestorsInsight Partners, B Capital, Radical Ventures, Salesforce Ventures, Workday Ventures

Harvey creates a generative AI platform tailored for elite law firms and in-house legal teams. Their system is designed to handle complex legal work, from research and analysis to drafting and document review.

Year Founded2022
FoundersGabe Pereyra, Winston Weinberg
Funding Amount$1B
Startup SizeLarge Team (251-1,000)
Last Funding StatusSeries F
Top InvestorsAndreessen Horowitz, OpenAI, Sequoia Capital, Coatue, Kleiner Perkins, Conviction, EQT Growth

90 Additional San Francisco Startups Worth Following

Our top ten picks are just the start of the story. A huge number of new companies are focused on AI, and they've collectively raised billions to build their ideas.

You'll see some that are brand new and others that are already well on their way. Here are the other startups defining what's next for San Francisco.

StartupIndustryYear FoundedAmount RaisedLast Funding Round
Mercor logo MercorAI2023$483.6MSeries C
BlockDAG logo BlockDAGCrypto2023$420MInitial Coin Offering
Nozomi Networks logo Nozomi NetworksSecurity2013$266MPrivate Equity
Momentum logo MomentumEnterprise2020$18MSeries A
Factory logo FactoryAI2023$70MSeries B
6sense logo 6senseAI2013$526MDebt Financing
Juniper Square logo Juniper SquareFintech2014$371MVenture Round
Assort Health logo Assort HealthAI2023$101.5MSeries B
Thinking Machines Lab logo Thinking Machines LabAI2025$2BSeed
Sierra logo SierraAI2023$635MVenture Round
Apollo.io logo Apollo.ioAI2015$251.3MSeries D
Exa logo ExaAI2021$107MSeries B
Strava logo StravaMedia2009$151.9MDebt Financing
TRM Labs logo TRM LabsData2018$149.9MSeries B
Distyl AI logo Distyl AIAI2022$202MSeries B
Ambience Healthcare logo Ambience HealthcareAI2020$319.3MSeries C
Periodic Labs logo Periodic LabsAI2025$300MSeed
Invisible Technologies logo Invisible TechnologiesData2015$107.9MVenture Round
Aven logo AvenMedia2019$252MSeries E
World logo WorldCrypto2019$379MUndisclosed
Honeycomb logo HoneycombCloud2016$146.9MSeries D
Kojo logo KojoManufacturing2018$93.6MSeries C
Zip logo ZipEnterprise2020$371.3MSeries D
Higgsfield logo HiggsfieldAI2022$58MSeries A
Motive logo MotiveAI2013$717.3MVenture Round
CyberCube logo CyberCubeAnalytics2015$285MVenture Round
Intercom logo IntercomSaaS2011$240.8MSeries D
Motion logo MotionAnalytics2019$73.3MSeries C
Aster logo AsterHealthcare2023$2.4MPre-Seed
Webflow logo WebflowSaaS2013$334.9MSeries C
Baseten logo BasetenAI2019$285MSeries D
Scale AI logo Scale AIAI2016$15.9BCorporate Round
Burnt logo BurntAI2022$4.3MSeed
Together AI logo Together AIAI2022$533.5MSeries B
LangChain logo LangChainAI2022$35MSeries A
Anything logo AnythingAI2021$19.5MSeries A
Framework logo FrameworkHardware2019$45MSeries A
Lakera logo LakeraAI2021$30MSeries A
Slope logo SlopeRetail2021$252.1MDebt Financing
Innovaccer logo InnovaccerAnalytics2014$654.1MSeries F
Audioshake logo AudioshakeAI2020$18.7MSeries A
Decagon logo DecagonAI2023$231MSeries C
Career Karma logo Career KarmaEducation2018$51.9MSeries B
Kong logo KongAI2017$344.1MSeries E
HappyRobot logo HappyRobotAnalytics2022$60.7MSeries B
Sentry logo SentryInfrastructure2012$217MSeries E
LambdaTest logo LambdaTestCloud2017$108MSeries D
Mesh logo MeshCrypto2020$124.5MVenture Round
Twelve Labs logo Twelve LabsAI2021$107.1MVenture Round
Greptile logo GreptileEnterprise2023$30.4MSeries A
Recall.ai logo Recall.aiAI2020$50.7MSeries B
Redis logo RedisAnalytics2011$356.8MSecondary Market
Cherry logo CherryRetail2017$94MSeries B
Medallion logo MedallionAutomation2020$128MSeries C
Tools For Humanity logo Tools For HumanityAI2019$115MSeries C
Verily logo VerilyAnalytics2015$3.5BGrant
Numeral logo NumeralEnterprise2022$57.5MSeries B
Nova Credit logo Nova CreditFintech2016$124.4MSeries C
PostHog logo PostHogAnalytics2020$182.2MSeries E
Pylon logo PylonAI2022$51.3MSeries B
Coalition logo CoalitionSecurity2017$800MCorporate Round
LMArena logo LMArenaAI2025$100MSeed
Substack logo SubstackMedia2017$200.2MSeries C
EcoFlow Tech logo EcoFlow TechEnergy2016$114.4MProduct Crowdfunding
Stable logo StableSaaS2019$1MSeries A
Unstoppable Domains logo Unstoppable DomainsCrypto2018$72MSeries A
Jasper logo JasperAI2021$131MSeries A
Phantom logo PhantomCrypto2021$268MSeries C
Fieldguide logo FieldguideFintech2020$50MSeries B
Laurel logo LaurelAI2016$155.7MSeries C
Hex Technologies logo Hex TechnologiesAnalytics2019$171.5MSeries C
ClassDojo logo ClassDojoEducation2011$191.1MVenture Round
Daymark Health logo Daymark HealthHealthcare2022$57.5MSeries A
Deepgram logo DeepgramAI2015$85.9MSeries B
Miro logo MiroEnterprise2011$476.3MSeries C
Cartography Biosciences logo Cartography BiosciencesBiotech2020$124MSeries B
Sonic logo SonicCrypto2020$16MVenture Round
Zed Industries logo Zed IndustriesMarketing2021$47.5MSeries B
Atomic logo AtomicRetail2020$55.1MVenture Round
Firecrawl logo FirecrawlAI2022$14.5MSeries A
Domino Data Lab logo Domino Data LabAnalytics2013$223.6MVenture Round
Gusto logo GustoFintech2011$746.1MVenture Round
Vanta logo VantaAI2018$503MSeries D
Armis logo ArmisEnterprise2015$837MSecondary Market
Flutterwave logo FlutterwaveFintech2016$474.5MSecondary Market
WorkWhile logo WorkWhileEducation2019$39.5MSeries B
Watershed logo WatershedCloud2019$239MSeries C
Incode Technologies logo Incode TechnologiesSecurity2015$257.1MSeries B
Varo Bank logo Varo BankMedia2015$1.1BSeries G
Automattic logo AutomatticMedia2005$985.9MSeries E

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