Santiago has become a center for new business growth. The city's startup scene shows tons of activity in fields ranging from energy and financial technology to software as a service.
Companies like HIF Global are leading in the energy sector, having raised $480M for its eFuel production. Others, such as the wellness platform Betterfly, have also secured major funding with $204.5M raised to date.
Below is our list of 29 Santiago startups worth keeping an eye on.
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Get the Sheet for $50HIF Global produces carbon-neutral eFuels that can power existing cars, ships, and planes without modifications. The company creates its synthetic gasoline substitute by combining green hydrogen with recycled carbon dioxide.
| Year Founded | 2019 |
| Founders | — |
| Funding Amount | $480M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Corporate Round |
| Top Investors | Baker Hughes, Porsche, EIG Global Energy Partners(EIG), Mitsui O.S.K. Lines, Idemitsu Kosan |
AgendaPro builds management software for businesses in the beauty and wellness industries to handle online bookings and payments. Their platform gives owners a single tool for scheduling appointments, charging customers, and managing client details.
| Year Founded | 2014 |
| Founders | Julio Guzmán, Matías Ulloa, Nicolás Rossi, Sebastián Hevia |
| Funding Amount | $42.8M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series B |
| Top Investors | Y Combinator, Riverwood Capital, Kayyak Ventures, Fen Ventures, CORFO |
Buk develops a comprehensive, cloud-based platform for human resource management. Their software centralizes a wide range of HR functions, including payroll, talent management, and employee benefits, into one unified system.
| Year Founded | 2016 |
| Founders | Felipe Sateler, Jaime Arrieta Boetsch, Ricardo Sateler, Santiago Lira, Teresita Moran Ovalle |
| Funding Amount | $135M |
| Startup Size | Major Organization (1,001-5,000) |
| Last Funding Status | Series B |
| Top Investors | Base10 Partners, Headline, Endeavor Catalyst, SoftBank, Workday Ventures |
Betterfly builds a purpose-driven wellbeing platform that converts healthy habits into charitable donations. Their system also rewards employees with life insurance coverage that grows at no cost as they engage in healthy activities.
| Year Founded | 2018 |
| Founders | Cristobal della Maggiora, Eduardo della Maggiora |
| Funding Amount | $204.5M |
| Startup Size | Large Team (251-1,000) |
| Last Funding Status | Series C |
| Top Investors | QED Investors, Endeavor Catalyst, Lightrock, VentureSouq, Greycroft |
Toku builds a payment recovery platform for subscription-based companies in Latin America. Their software automates the collection process to reduce customer churn and recover revenue from failed payments.
| Year Founded | 2020 |
| Founders | Cristina Etcheberry, Francisca Noguera Astaburuaga |
| Funding Amount | $66.5M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series A |
| Top Investors | Oak HC/FT, Y Combinator, Clocktower Technology Ventures, F-Prime, FundersClub |
Engie Energia Chile generates and supplies electricity throughout the country and manages natural gas transportation. They operate a diverse portfolio that includes both conventional energy infrastructure and a growing number of renewable energy projects.
| Year Founded | 1981 |
| Founders | — |
| Funding Amount | $400M |
| Startup Size | Major Organization (1,001-5,000) |
| Last Funding Status | Debt Financing |
| Top Investors | International Finance Corporation, ILX |
PhageLab develops bacteriophage-based solutions to control bacterial diseases in animal production. Their technology provides a natural alternative to antibiotics, helping to improve both animal welfare and food safety.
| Year Founded | 2009 |
| Founders | Diego Belmar, Hans Pieringer, Nico Ferre, Nicolas Ferreira, Pablo Cifuentes |
| Funding Amount | $41M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Venture Round |
| Top Investors | Kaszek, Collaborative Fund, The Yield Lab LATAM, Start-Up Chile, Humboldt Fund |
Colektia builds a digital platform that helps financial institutions create new collections models based on artificial intelligence. Their software is designed to automate and optimize the debt recovery process through more efficient digital strategies.
| Year Founded | 2018 |
| Founders | Gabriel Monroy, Oswaldo Monroy |
| Funding Amount | $14.1M |
| Startup Size | Large Team (251-1,000) |
| Last Funding Status | Series B |
| Top Investors | Endeavor, Wayra, Village Capital, devlabs, Angel Ventures |
Wherex builds an AI-driven platform that automates the procurement process for B2B companies. Their software cuts down on repetitive tasks, allowing procurement teams to focus on more strategic, high-impact decisions.
| Year Founded | 2016 |
| Founders | Benjamin Garcia, Felipe Manterola Gana, Francisco Puente, Juan Carlos Hurtado Cruzat |
| Funding Amount | $7.5M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Seed |
| Top Investors | FJ Labs, Kayyak Ventures, Wollef Ventures, Tuesday Capital, DVC |
Talana created a Human Capital Management platform to help companies manage their workforce more efficiently. The software integrates key functions like payroll processing and digital signatures into one easy-to-use system.
| Year Founded | 2016 |
| Founders | José Antonio Akel, Pablo de la Barra |
| Funding Amount | $8.1M |
| Startup Size | Large Team (251-1,000) |
| Last Funding Status | Venture Round |
| Top Investors | Start-Up Chile, Altis, Venturance Alternative Assets, Venturance |
19 Additional Santiago Startups Worth Following
Our top picks only scratch the surface of what’s happening in Santiago. Founders are tackling big challenges in fields like fintech and agtech, and have raised over $140 million to grow their ideas.
Some companies are just getting started, while others are already scaling up. Here’s a look at more startups that are shaping the city's ecosystem.