St. Louis provides a focused environment for startups, with programs covering a range of industries, like FinTech, bioscience, and sports technology.
SixThirty has made over 170 investments in financial and security tech. The Skandalaris Center and Capital Innovators have also been active, backing over 150 and 130 companies respectively.
Below is our list of the best 10 accelerators and incubators in St Louis.
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2,189 Accelerators & Incubators
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1,600+ Unicorns
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250 BioTech & Health Investors
List of startup investors in the BioTech, Health, and Medicine industries, along with their Twitter, LinkedIn, and email addresses.
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250 AI Investors
List of 250 startup investors in the AI and Machine Learning industries, along with their Twitter, LinkedIn, and email addresses.
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250 Fintech Investors
List of 250 startup investors in the FinTech and Finance industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50SixThirty fuels the growth of late seed-stage startups with capital and a hands-on accelerator program. Their expertise is concentrated on building and scaling companies in the complex worlds of FinTech, InsurTech, and Cyber Security.
| Year Founded | 2013 |
| Founders | Brian Matthews, Atul Kamra, Jim McKelvey |
| Investment Amount | $100K |
| Equity Taken | Negotiated % |
| Nº of Investments | 177 |
| Nº of Exits | 32 |
| Program Type | On-Site |
| Duration (Weeks) | 14 |
Acting as the central hub for innovation at Washington University, the Skandalaris Center helps bring entrepreneurial ideas from the campus community to life. They specialize in fostering interdisciplinary teams, providing them with the foundational resources and mentorship to launch and grow their ventures.
| Year Founded | 2001 |
| Founders | II Luscri |
| Nº of Investments | 151 |
| Nº of Exits | 13 |
Stadia Ventures runs a dedicated accelerator for startups innovating within the sports and esports industries. They provide founders with a $100K equity investment and connect them to a global network of mentors and investors.
| Year Founded | 2015 |
| Founders | Art Chou, Tim Hayden |
| Investment Amount | $100K equity investment per company |
| Nº of Investments | 76 |
| Nº of Exits | 11 |
| Program Type | On-Site |
| Duration (Weeks) | 14 |
As a venture development organization, BioGenerator fuels the growth of early-stage bioscience companies with crucial seed funding and strategic support. They specialize in nurturing startups in the healthcare and agriculture industries, helping to transform scientific breakthroughs into viable businesses.
| Year Founded | 2003 |
| Founders | Tom Cohen, Matt Helms |
| Nº of Investments | 78 |
| Nº of Exits | 9 |
Through a nationally recognized accelerator and direct seed funds, Capital Innovators invests in promising tech-enabled startups. They primarily back companies in the consumer goods and enterprise spaces, providing them with crucial early-stage capital and resources.
| Year Founded | 2011 |
| Founders | Judy Sindecuse |
| Nº of Investments | 138 |
| Nº of Exits | 8 |
| Duration (Weeks) | 13 |
Through its partnership with Ameren Corporation, this program provides seed funding and mentorship to startups developing next-generation energy solutions. Founders receive hands-on guidance from industry experts and access to corporate resources to help build and scale technologies for the modern energy grid.
| Year Founded | 2017 |
| Founders | — |
| Nº of Investments | 11 |
| Nº of Exits | 2 |
To help close the funding gap for female founders, Prosper Women Entrepreneurs provides direct access to growth capital. This for-profit organization supports startups in the consumer goods and IT sectors, preparing them for investment and scale.
| Year Founded | 2014 |
| Founders | Peter Finley, Maxine Clark, Jennifer Ehlen, Hal Gentry, Mary Jo Gorman, Carol Matthews |
| Nº of Investments | 34 |
| Nº of Exits | 1 |
| Program Type | On-Site |
| Duration (Weeks) | 11 |
WEPOWER works to build economic and political power for Black and Latinx communities in St. Louis. Through their business accelerator, they equip entrepreneurs with coaching and capital, while simultaneously mobilizing community members to design more just and equitable public systems.
| Year Founded | 2018 |
| Founders | — |
| Nº of Investments | 20 |
| Nº of Exits | 1 |
As a technology investment fund, Equity.com provides capital to startups across diverse industries including FinTech, IT, and non-profits. Their core philosophy is to invest in people rather than just ideas, with a team of experienced founders offering mentorship to help scale portfolio companies like Answers.com.
| Year Founded | 2017 |
| Founders | Chris Sims, David Karandish |
| Nº of Investments | 4 |
| Nº of Exits | — |
Sling Health brings together multidisciplinary student teams to invent and develop solutions for pressing clinical needs. They provide the necessary training, mentorship, and resources to help these budding entrepreneurs turn their ideas into viable biotech ventures.
| Year Founded | 2013 |
| Founders | — |
| Nº of Investments | 1 |
| Nº of Exits | — |