Top 7 Philadelphia Startups to Watch in 2026
Philadelphia has become a key location for startups in the healthcare and biotechnology sectors. The city is home to many companies developing new medical software and life science treatments.
Recent examples include Dispatch Bio, which secured $216M for its cancer immunotherapy research. Tendo also raised $187.6M to build new software for patient and clinician connections.
Below is our list of 7 Philadelphia startups worth keeping an eye on.
Failory's Top 7 Picks
Proscia develops digital pathology software that helps laboratories and life sciences organizations manage and analyze pathology data. Their AI-powered Concentriq® platform is used to accelerate discoveries and improve patient outcomes in cancer research and diagnosis.
| Year Founded | 2014 |
| Founders | Coleman Stavish, David West, Nathan Buchbinder |
| Funding Amount | $129.8M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series D |
| Top Investors | Insight Partners, Hitachi Ventures, Fusion Fund, Flybridge, Alpha Intelligence Capital |
Tendo develops a software platform that serves as a central connection point between patients, clinicians, and caregivers. Their technology is designed to create a more seamless and engaging healthcare journey for all parties.
| Year Founded | 2020 |
| Founders | Dan Goldsmith, Jennifer Goldsmith |
| Funding Amount | $187.6M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Venture Round |
| Top Investors | General Catalyst, Lux Capital, Jefferson Health System |
Interius BioTherapeutics develops a proprietary platform for in vivo cell and gene therapy, a new approach to treatment. The company's technology engineers therapeutic cells directly inside the patient's body, with an initial focus on treating blood cancers.
| Year Founded | 2019 |
| Founders | Bruce A. Peacock, Saar Gill |
| Funding Amount | $175.9M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Undisclosed |
| Top Investors | RA Capital Management, Cormorant Asset Management, Bain Capital Life Sciences, Longwood Fund, Agent Capital |
HealthVerity has built a platform for discovering, licensing, and connecting a wide range of healthcare data. Their technology helps organizations access real-world data to support clinical trials, research, and commercial operations.
| Year Founded | 2014 |
| Founders | Andrew Goldberg, Andrew Kress |
| Funding Amount | $142.2M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series D |
| Top Investors | Greycroft, Flare Capital Partners, Foresite Capital, Durable Capital Partners |
Asylon Robotics builds an automated security platform that uses both drones and ground robots to monitor and secure large perimeters. Their systems are designed to provide 24/7 autonomous surveillance and a robotic first response to potential threats.
| Year Founded | 2015 |
| Founders | Adam Mohamed, Brent McLaughlin, Damon Henry |
| Funding Amount | $26.8M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series B |
| Top Investors | GO PA Fund, Insight Partners, Decisive Point, Leonid Capital Partners, Veteran Ventures Capital |
Dispatch Biotherapeutics develops novel immunotherapies specifically engineered to target and treat solid tumors. This work could represent a significant advancement in cancer care for patients with difficult-to-treat malignancies.
| Year Founded | 2022 |
| Founders | — |
| Funding Amount | $216M |
| Startup Size | Mid-Size Team (51-250) |
| Last Funding Status | Series A |
| Top Investors | ARCH Venture Partners, Bristol-Myers Squibb, University of Pennsylvania, Stanford University, Alexandria Venture Investments |
ConnectDER builds a meter collar that simplifies connecting distributed energy resources, like solar, to the grid. Their technology helps reduce installation costs and accelerate the adoption of clean energy for homeowners.
| Year Founded | 2011 |
| Founders | Whitman Fulton |
| Funding Amount | $80.3M |
| Startup Size | Lean Team (11-50) |
| Last Funding Status | Series D |
| Top Investors | Elemental Impact, Clean Energy Ventures, MassMutual Ventures, Energy Innovation Capital, US Department of Energy |
