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The United States startup scene is heavily focused on artificial intelligence. Companies like OpenAI and Anthropic have raised a combined total of over $100 billion.
Other fields like fintech and robotics are also growing, with firms securing large investments. The full ranking shows the top 100 companies currently leading the American market.
Below is our list of 100 United States startups worth keeping an eye on.
Everything you need to raise funding for your startup, including 3,500+ investors, 7 tools, 18 templates and 3 learning resources.
Buy It For $97 $297 →Information about the industries, countries, and cities they generally invest in.
Get the Sheet for $50Information about their valuation, HQ's location, founded year, name of founders, funding amount and number of employees.
Get the Sheet for $50List of startup investors in the BioTech, Health, and Medicine industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50List of 250 startup investors in the AI and Machine Learning industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50List of 250 startup investors in the FinTech and Finance industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50Anthropic builds large-scale AI systems with a focus on safety and research. Their work centers on creating reliable and steerable models, like the Claude family of products, designed to be helpful and harmless.
Perplexity has developed an AI-powered answer engine that provides accurate, real-time responses to user questions. Their platform combines the capabilities of a search engine with a conversational interface to deliver cited, reliable information.
xAI develops artificial intelligence with the ambitious goal of helping humanity understand the true nature of the universe. Their first model, Grok, is a conversational AI that has real-time access to information from the 𝕏 platform.
Replit created a collaborative, browser-based platform for software development that features an integrated AI coding assistant. Their all-in-one environment enables developers to write code, deploy applications, and host websites directly from a single interface.
OpenAI develops advanced AI models, including the popular conversational tool ChatGPT. The AI research and deployment company aims to ensure that artificial general intelligence benefits all of humanity.
ElevenLabs develops generative AI models for creating lifelike, human-sounding speech from text. Their platform is widely used by content creators and developers for tasks ranging from voice cloning to automated dubbing.
Figure builds autonomous humanoid robots to work in commercial settings like manufacturing and logistics. Their first robot, Figure 01, is designed to handle a range of physical jobs, helping companies address labor shortages and improve workplace safety.
Polymarket operates a prediction market where users trade on the outcomes of real-world events. The platform allows people to speculate on future happenings in categories like politics, finance, and pop culture, with trades settled on the blockchain.
Stripe builds a suite of APIs that power online payment processing and commerce solutions for internet businesses. Their financial infrastructure platform allows companies of all sizes to easily accept payments, send payouts, and manage their operations online.
MoonPay builds the financial plumbing that makes it simple to buy and sell digital assets like cryptocurrencies and NFTs. Their on-and-off-ramp technology powers the payment experience for many of the world's leading crypto wallets, marketplaces, and applications.
Our top ten picks are just a small slice of the activity happening across the country. Everywhere you look, founders are experimenting with new ideas and bringing them to life.
Many are focused on AI, and together these companies have raised tens of billions of dollars. Below is a look at 90 more startups that are shaping the future of their industries.
| Startup | Industry | Year Founded | Amount Raised | Last Funding Round |
|---|---|---|---|---|
| AI | 2019 | $768.2M | Series F | |
| AI | 2017 | $391.9M | Series E | |
| AI | 2022 | $3.4B | Series D | |
| AI | 2023 | $896M | Series C | |
| Infrastructure | 2017 | $575M | Debt Financing | |
| Analytics | 2013 | $21.8B | Venture Round | |
| Media | 2020 | $326M | Series C | |
| AI | 2025 | $65M | Debt Financing | |
| Security | 2021 | $925M | Series B | |
| AgTech | 2014 | $1.4B | Venture Round | |
| Analytics | 2016 | $142.8M | Series B | |
| AI | 2022 | $1B | Series E | |
| Security | 2017 | $187.8M | Series C | |
| Media | 2007 | $683M | Undisclosed | |
| Crypto | 2018 | $477M | Debt Financing | |
| AI | 2016 | $466.5M | Series E | |
| Manufacturing | 2015 | $178.8M | Series C | |
| AI | 2021 | $243M | Series C | |
| AI | 2020 | $195M | Series C | |
| Energy | 2017 | $2.9B | Series B | |
| AI | 2020 | $94.3M | Series B | |
| Enterprise | 2015 | $216.7M | Series C | |
| Crypto | 2013 | $171.5M | Corporate Round | |
| Healthcare | 2014 | $625M | Debt Financing | |
| AI | 2023 | $483.6M | Series C | |
| Media | 2021 | $150.1M | Series A | |
| Crypto | 2023 | $420M | Initial Coin Offering | |
| Mobility | 2017 | $1.8B | Corporate Round | |
| AI | 2022 | $53.5M | Series A | |
| Security | 2013 | $266M | Private Equity | |
| Crypto | 2015 | $282.1M | Series D | |
| AI | 2023 | $87.6M | Series B | |
| Enterprise | 2020 | $18M | Series A | |
| Security | 2021 | $612M | Series D | |
| AI | 2021 | $317M | Series B | |
| Hardware | 2014 | $262.1M | Series D | |
| Fintech | 2015 | $204.8M | Debt Financing | |
| Fashion | 2019 | $701M | Series C | |
| AI | 2012 | $1.7B | Debt Financing | |
| AI | 2009 | $386.3M | Venture Round | |
| Cloud | 2013 | $415M | Series E | |
| AI | 2016 | $253.3M | Series C | |
| Security | 2013 | $292.2M | Series E | |
| AI | 2022 | $125M | Series B | |
| AI | 2023 | $70M | Series B | |
| Travel | 2015 | $2.2B | Convertible Note | |
| Fintech | 2012 | $280.6M | Series D | |
| Media | 2021 | $36M | Series A | |
| AI | 2013 | $526M | Debt Financing | |
| Food | 2015 | $39.2M | Series B | |
| Biotech | 2016 | $1.3B | Venture Round | |
| Biotech | 2021 | $568.1M | Series C | |
| SaaS | 2014 | $268M | Private Equity | |
| AI | 2017 | $202M | Series C | |
| Enterprise | 2019 | $557.6M | Series B | |
| Fintech | 2022 | $24.8M | Series A | |
| Mobility | 2017 | $309.6M | Corporate Round | |
| Sports | 2007 | $416.2M | Series E | |
| AI | 2016 | $431.8M | Corporate Round | |
| Fintech | 2014 | $371M | Venture Round | |
| AI | 2021 | $26.7M | Seed | |
| AI | 2023 | $101.5M | Series B | |
| AI | 2022 | $8.9M | Seed | |
| Media | 2022 | $88M | Seed | |
| Manufacturing | 2017 | $655.6M | Series F | |
| AI | 2025 | $2B | Seed | |
| AI | 2023 | $635M | Venture Round | |
| Biotech | 2021 | $700M | Series D | |
| AI | 2023 | $293.2M | Series A | |
| Media | 2018 | $544.5M | Series D | |
| Fintech | 2014 | $3.6B | Undisclosed | |
| Analytics | 2021 | $153.4M | Series C | |
| AI | 2015 | $251.3M | Series D | |
| AI | 2016 | $381M | Series E | |
| Healthcare | 2021 | $152M | Series C | |
| Infrastructure | 2021 | $6.5B | Grant | |
| Infrastructure | 2019 | $454.5M | Secondary Market | |
| AI | 2021 | $107M | Series B | |
| Media | 2009 | $151.9M | Debt Financing | |
| AI | 2023 | $435M | Series A | |
| Energy | 2009 | $1B | Private Equity | |
| Cloud | 2021 | $129.6M | Venture Round | |
| AI | 2017 | $75.1M | Series B | |
| Security | 2014 | $498.3M | Series C | |
| Data | 2018 | $149.9M | Series B | |
| AI | 2022 | $202M | Series B | |
| AI | 2023 | $18M | Series A | |
| AI | 2020 | $319.3M | Series C | |
| AI | 2021 | $1.3B | Series E | |
| AI | 2025 | $300M | Seed |
