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San Mateo is a central hub within Silicon Valley's technology landscape. The city hosts a variety of companies specializing in fields like artificial intelligence and financial technology.
Among them is AI drone company Skydio, which has raised $740M in funding. Another recent addition is Aurasell, a 2024 startup that secured a $30M seed round.
Below is our list of 38 San Mateo startups worth keeping an eye on.
Everything you need to raise funding for your startup, including 3,500+ investors, 7 tools, 18 templates and 3 learning resources.
Buy It For $97 $297 →Information about the industries, countries, and cities they generally invest in.
Get the Sheet for $50Information about their valuation, HQ's location, founded year, name of founders, funding amount and number of employees.
Get the Sheet for $50List of startup investors in the BioTech, Health, and Medicine industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50List of 250 startup investors in the AI and Machine Learning industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50List of 250 startup investors in the FinTech and Finance industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50FalconX provides a digital assets prime brokerage with trading, financing, and custody services for institutional clients. Their platform offers comprehensive access to global cryptocurrency liquidity for the world's leading institutions.
Skydio develops highly autonomous drones powered by artificial intelligence for complex tasks. These flying robots are used across consumer, enterprise, and government sectors for everything from creative filming to critical inspections.
SnapLogic builds an intelligent integration platform that helps enterprises connect their various applications and data sources. Their platform provides a low-code environment for automating business processes and managing data across both cloud and on-premise systems.
QuSecure builds software to protect enterprise and government clients from the security threats posed by quantum computing. Their core platform orchestrates post-quantum cryptography across an organization's existing network to make it quantum-resilient.
Notable builds an AI platform that automates administrative and clinical workflows for healthcare providers. Their technology connects with electronic health records to identify the next best action for any patient, reducing the administrative burden on staff.
Aurasell is building an AI-native platform that manages the entire go-to-market process for sales and operations teams. Their software automates workflows and generates insights to help companies drive revenue growth from lead to close.
Sendbird builds a communication platform that allows companies to add messaging, voice, and video features into their own apps and websites. The platform combines developer-friendly APIs with AI-powered tools to help businesses create modern customer service experiences.
Luminary Cloud has developed a Physics AI platform that helps engineers accelerate the design and optimization of physical products. Their software uses AI to run complex simulations, allowing for faster design cycles and more thorough product exploration.
Hammerspace develops a data platform that eliminates access delays for teams working in AI and high-performance computing. It unifies data across disparate storage systems and locations into a single global namespace, making files accessible to any application.
Helix operates a platform for population genomics, helping to bridge the gap between genetic research and clinical applications. They provide health systems and life science companies with the tools to implement large-scale genomic screening and research programs.
Our top ten picks only scratch the surface of what's happening in San Mateo. Many other founders are focused on fields like AI and analytics, and have raised over $3 billion combined.
Some companies are just getting started, while others are already well on their way. Here’s a look at the rest of the startups shaping the local ecosystem.
| Startup | Industry | Year Founded | Amount Raised | Last Funding Round |
|---|---|---|---|---|
| Hardware | 2015 | $73.7M | Venture Round | |
| AI | 2023 | $44.5M | Series A | |
| Fintech | 2019 | $4M | Series A | |
| Security | 1999 | $592M | Private Equity | |
| Analytics | 2023 | $23M | Seed | |
| Data | 2011 | $256.1M | Private Equity | |
| AI | 2016 | $102.2M | Series C | |
| Analytics | 2007 | $805.1M | Private Equity | |
| Gaming | 2015 | $67.3M | Series C | |
| Sports | 2020 | $27M | Series A | |
| AgTech | 2022 | $37M | Series A | |
| Enterprise | 2019 | $35M | Series A | |
| Marketing | 2007 | $50M | Venture Round | |
| Retail | 2015 | $122M | Series D | |
| Cloud | 2011 | $80.3M | Series C | |
| Analytics | 2017 | $463M | Series C | |
| AI | 2020 | $21.5M | Series A | |
| AI | 2019 | $99.3M | Series B | |
| Education | 2015 | $80.8M | Debt Financing | |
| Infrastructure | 2022 | $21.8M | Series A | |
| Analytics | 2012 | $259M | Series E | |
| Fintech | 2020 | $27.2M | Venture Round | |
| AI | 2018 | $67M | Series B | |
| Analytics | 2015 | $73M | Series C | |
| AI | 2023 | $7.7M | Seed | |
| Infrastructure | 2020 | $8.8M | Seed | |
| Biotech | 2019 | $242.2M | Series C | |
| Healthcare | 2014 | $198.3M | Venture Round |
