This free sheet contains 100 accelerators and incubators you can apply to today, along with information about the industries they generally invest in.
This free sheet contains all the information about the top 100 unicorns, including their valuation, HQ's location, founded year, name of founders, funding amount and number of employees.
This free Notion document contains the best 100+ resources you need for building a successful startup, divided in 4 categories: Fundraising, People, Product, and Growth.
Missouri's startup ecosystem shows a wide range of industries, from biotechnology to artificial intelligence. The state is home to both new businesses and long-established companies.
There is access to significant funding, with firms like EquipmentShare raising $3.5 billion. The environment includes mature companies like Lead, founded in 1928, and recent startups like Trially, which began in 2023.
Below is our list of 20 Missouri startups worth keeping an eye on.
Everything you need to raise funding for your startup, including 3,500+ investors, 7 tools, 18 templates and 3 learning resources.
Buy It For $97 $297 →Information about the industries, countries, and cities they generally invest in.
Get the Sheet for $50Information about their valuation, HQ's location, founded year, name of founders, funding amount and number of employees.
Get the Sheet for $50List of startup investors in the BioTech, Health, and Medicine industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50List of 250 startup investors in the AI and Machine Learning industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50List of 250 startup investors in the FinTech and Finance industries, along with their Twitter, LinkedIn, and email addresses.
Get the Sheet for $50Lead Bank builds a Banking as a Service platform that gives fintech companies the tools to create their own financial products. Operating as a nationally chartered bank, they provide the core infrastructure and payment solutions needed to power these new applications.
Capacity develops an AI-powered support automation platform that connects an entire tech stack to a single dashboard. Their tools are used to answer questions, automate tedious processes, and build custom solutions for both employees and customers.
Trially builds an AI-native platform that matches, engages, and enrolls patients for clinical trials. Their system achieves this with roughly 95% accuracy and at breakthrough speed, significantly accelerating the recruitment process.
BizzyCar built an AI-driven platform for the automotive industry that automates the complex process of service recall management. Their software simplifies maintenance workflows for dealerships, helping them connect with car owners more effectively.
Wugen develops off-the-shelf cellular therapies to treat both solid tumors and hematologic malignancies. Their work centers on using memory natural killer (NK) cells and CAR-T technologies to build a pipeline of readily available cancer treatments.
TierPoint offers a range of secure and connected IT platform solutions from its national footprint of data centers. They specialize in helping enterprises manage their complex IT infrastructure through colocation, cloud, and recovery services.
EquipmentShare gives construction companies a unified way to manage their fleet through its T3 operating system. They pair this smart jobsite technology with a nationwide network for equipment rentals, sales, and service.
Edward Jones delivers personalized financial advising, wealth management, and brokerage services through its extensive network of local advisors. The firm focuses on building personal relationships with clients to develop tailored, long-term investment strategies.
C2N Diagnostics develops advanced blood tests for the early detection of neurodegenerative diseases, including Alzheimer's. Their PrecivityAD line of diagnostics helps physicians identify brain amyloid plaques, offering a less invasive alternative to traditional methods.
Geneoscopy develops a noninvasive screening test for colorectal cancer that analyzes biomarkers from stool samples. Their technology provides a patient-friendly alternative to traditional colonoscopies for early detection.
The top 10 are just a small slice of what’s happening across Missouri right now. New companies are popping up in fields as different as AI, education, and fintech.
Combined, this next group of startups has raised over $700 million. Here’s a look at more of the companies that make the state's tech scene so interesting.
| Startup | Industry | Year Founded | Amount Raised | Last Funding Round |
|---|---|---|---|---|
| AI | 2018 | $5M | Seed | |
| Enterprise | 2015 | $1.5M | Private Equity | |
| Enterprise | 2000 | $325.3M | Series A | |
| Fintech | 2013 | $194.5M | Venture Round | |
| Healthcare | 2020 | $28M | Series A | |
| Education | 2007 | $107M | Grant | |
| Media | 2017 | $24.1M | Series B | |
| Mobility | 2012 | $35.4M | Grant | |
| Nonprofit | 2017 | $15M | Debt Financing | |
| Nonprofit | 2016 | $1.6M | Grant |
